New gel aims to heal fragile skin in blistering disease

NCT ID NCT07027345

First seen Nov 01, 2025 · Last updated Apr 15, 2026 · Updated 21 times

Summary

This study is testing whether a gel called TolaSure can help control symptoms of epidermolysis bullosa simplex (EBS), a genetic condition that causes fragile, blistering skin. 40 patients, including children as young as 4, will apply the gel or a placebo to their skin daily for two months, then all will use the active gel for another two months. Researchers will measure changes in blister size, pain, itch, and quality of life to see if the gel is safe and effective.

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Contacts and locations

Locations

  • NU Dermatolgy CTU

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University School of Medicine, Dermatology Department

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.