Race to stop myeloma before it starts: major trial tests early drug combo

NCT ID NCT04270409

Ongoing Prevention Sponsor: Sanofi Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new drug called isatuximab to a standard two-drug combination can delay or prevent high-risk smoldering multiple myeloma from progressing to active, symptomatic disease. It will involve about 337 patients who have the high-risk early form of the blood cancer but do not yet have symptoms. The goal is to see if the three-drug combination keeps patients healthier for longer compared to the standard two-drug treatment alone.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Cancer Specialist of North Florida Site Number : 8400011

Jacksonville, Florida, 32256, United States
Colorado Blood Cancer Institute Site Number : 8400007

Denver, Colorado, 80218, United States
Dana Farber Cancer Institute Site Number : 8400001

Boston, Massachusetts, 02115, United States
Investigational Site Number : 2030001

Prague, 12808, Czechia
Investigational Site Number : 2030002

Olomouc, 77900, Czechia
Investigational Site Number : 2030003

Ostrava - Poruba, 70852, Czechia
Investigational Site Number : 2030004

Brno, 62500, Czechia
Investigational Site Number : 2030005

Hradec Králové, 50005, Czechia
Investigational Site Number : 7920001

Ankara, 06620, Turkey (Türkiye)
Investigational Site Number : 7920002

Istanbul, 34390, Turkey (Türkiye)
Investigational Site Number : 7920003

Izmir, 35040, Turkey (Türkiye)
Investigational Site Number : 7920004

Istanbul, 34214, Turkey (Türkiye)
Investigational Site Number : 7920005

Ankara, 06010, Turkey (Türkiye)
Investigational Site Number :0360001

Wollongong, New South Wales, 2500, Australia
Investigational Site Number :0360002

Fitzroy, Victoria, 3065, Australia
Investigational Site Number :0360004

Richmond, Victoria, 3121, Australia
Investigational Site Number :0360005

Waratah, New South Wales, 2298, Australia
Investigational Site Number :0360006

Nedlands, Western Australia, 6009, Australia
Investigational Site Number :0360007

Heidelberg West, Victoria, 3081, Australia
Investigational Site Number :0360008

Liverpool, New South Wales, 2170, Australia
Investigational Site Number :0760002

São Paulo, São Paulo, 04537-081, Brazil
Investigational Site Number :1240001

Montreal, Quebec, H1T 2M4, Canada
Investigational Site Number :1240004

Edmonton, Alberta, T6G 1Z2, Canada
Investigational Site Number :1240005

Moncton, New Brunswick, E1C 6Z8, Canada
Investigational Site Number :1560001

Tianjin, 300020, China
Investigational Site Number :1560002

Hangzhou, 310003, China
Investigational Site Number :1560003

Hangzhou, 310003, China
Investigational Site Number :1560004

Shanghai, 200032, China
Investigational Site Number :1560005

Shenyang, 110022, China
Investigational Site Number :1560006

Nanchang, 330006, China
Investigational Site Number :2080001

Aalborg, 9000, Denmark
Investigational Site Number :2080002

Roskilde, 4000, Denmark
Investigational Site Number :2080003

Aarhus N, 8200, Denmark
Investigational Site Number :2080005

Copenhagen, 2100, Denmark
Investigational Site Number :2500001

Rennes, 35033, France
Investigational Site Number :2500002

Poitiers, 86021, France
Investigational Site Number :2500003

Lille, 59037, France
Investigational Site Number :2500005

Paris, 75012, France
Investigational Site Number :2500006

La Roche-sur-Yon, 85925, France
Investigational Site Number :2500007

Grenoble, 38043, France
Investigational Site Number :2500009

Ars-Laquenexy, 57085, France
Investigational Site Number :2500010

Bayonne, 64109, France
Investigational Site Number :2500011

Paris, 75013, France
Investigational Site Number :2760001

Hamburg, 20246, Germany
Investigational Site Number :2760002

Heidelberg, 69120, Germany
Investigational Site Number :3000001

Athens, 11528, Greece
Investigational Site Number :3000002

Athens, 10676, Greece
Investigational Site Number :3000003

Thessaloniki, PC 54007, Greece
Investigational Site Number :3480001

Budapest, 1097, Hungary
Investigational Site Number :3480002

Debrecen, 4032, Hungary
Investigational Site Number :3480003

Budapest, 1083, Hungary
Investigational Site Number :3480004

Kaposvár, 7400, Hungary
Investigational Site Number :3720001

Dublin, Dublin, Ireland
Investigational Site Number :3720002

Dublin, Dublin, Ireland
Investigational Site Number :3720003

Dublin, Dublin, Ireland
Investigational Site Number :3760001

Jerusalem, 91031, Israel
Investigational Site Number :3760002

Jerusalem, 91120, Israel
Investigational Site Number :3760003

Tel Aviv, 64239, Israel
Investigational Site Number :3760004

Ashdod, 7747629, Israel
Investigational Site Number :3760005

Petah Tikva, 49100, Israel
Investigational Site Number :3760006

Ramat Gan, 5265601, Israel
Investigational Site Number :3800001

Rozzano, Milano, 20089, Italy
Investigational Site Number :3800002

Terni, 05100, Italy
Investigational Site Number :3800003

Bologna, 40138, Italy
Investigational Site Number :3800005

Ancona, 60032, Italy
Investigational Site Number :3800006

Meldola, Forlì-Cesena, 47014, Italy
Investigational Site Number :3920001

Shibuya-ku, Tokyo, 150-8935, Japan
Investigational Site Number :3920002

Nagoya, Aichi-ken, 467-8602, Japan
Investigational Site Number :3920003

Okayama, Okayama-ken, 701-1192, Japan
Investigational Site Number :3920005

Higashiibaraki-gun, Ibaraki, 311-3193, Japan
Investigational Site Number :3920006

Kamogawa-shi, Chiba, 296-8602, Japan
Investigational Site Number :3920008

Maebashi, Gunma, 371-8511, Japan
Investigational Site Number :3920009

Sunto-gun, Shizuoka, 411-8777, Japan
Investigational Site Number :4100001

Seoul, Seoul-teukbyeolsi, 03722, South Korea
Investigational Site Number :4100002

Seoul, 06591, South Korea
Investigational Site Number :4100003

Seoul, Seoul-teukbyeolsi, 03080, South Korea
Investigational Site Number :4100004

Gangnam-gu, Seoul-teukbyeolsi, 06351, South Korea
Investigational Site Number :4400001

Vilnius, 08661, Lithuania
Investigational Site Number :5540001

Hamilton, Waikato Region, 3204, New Zealand
Investigational Site Number :5540004

Christchurch, Canterbury, New Zealand
Investigational Site Number :5780001

Oslo, 0450, Norway
Investigational Site Number :5780002

Bergen, 5021, Norway
Investigational Site Number :6160002

Lodz, Lódzkie, 93-510, Poland
Investigational Site Number :6160005

Chorzów, Silesian Voivodeship, 41-500, Poland
Investigational Site Number :6160006

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-168, Poland
Investigational Site Number :6160008

Gdansk, Pomeranian Voivodeship, 80-214, Poland
Investigational Site Number :7240001

Barcelona, Barcelona [Barcelona], 08041, Spain
Investigational Site Number :7240002

Valencia, Valenciana, Comunidad, 46017, Spain
Investigational Site Number :7240003

Zaragoza, 50009, Spain
Investigational Site Number :7240004

Barcelona, Barcelona [Barcelona], 08036, Spain
Investigational Site Number :7240005

Madrid, 28041, Spain
Investigational Site Number :7240006

Pamplona, Navarre, 31008, Spain
Investigational Site Number :7240007

Salamanca, 37007, Spain
Investigational Site Number :7520001

Gothenburg, 413 45, Sweden
Investigational Site Number :7520003

Helsingborg, 251 87, Sweden
Investigational Site Number :8260001

Leicester, LE15WW, United Kingdom
Investigational Site Number :8260002

Bournemouth, Hampshire, BH7 7DW, United Kingdom
Investigational Site Number :8260003

London, London, City of, SE1 7EH, United Kingdom
Investigational Site Number :8260004

Southampton, SO16 6YD, United Kingdom
Novant Health Forsyth Medical Center Site Number : 8401015

Winston-Salem, North Carolina, 27103, United States
Presbyterian Hospital Site Number : 8400015

Charlotte, North Carolina, 28204, United States
Tennessee Oncology Site Number : 8400006

Nashville, Tennessee, 37203, United States
UCLA Site Number : 8400010

Los Angeles, California, 90024, United States
University of Miami Site Number : 8400012

Miami, Florida, 33136, United States
~University of Texas - MD Anderson Cancer Center Site Number : 8400002

Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.

PLASMA CELL MYELOMA