Striking first: new trial attacks leukemia before it strikes back

NCT ID NCT03766763

Summary

This trial is testing whether giving a targeted drug called venetoclax early can control high-risk chronic lymphocytic leukemia (CLL) in patients who have the disease but no major symptoms yet. The study involves 82 adults with specific high-risk features in their early-stage CLL. The main goal is to see if this preemptive treatment leads to a deep response, measured by very low levels of remaining cancer cells after one year.

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Contacts and locations

Locations

  • Bordeaux Pessac

    Pessac, 33604, France

  • CH BLOIS

    Blois, 41000, France

  • CHU CAEN

    Caen, 14033, France

  • Centre Henri Becquerel - Service Hématologie Clinique

    Rouen, 76038, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Centre Hospitalier Regional Metz Thionville

    Metz, 57085, France

  • Centre leon berard

    Lyon, 69008, France

  • Ch Annecy

    Annecy, 74374, France

  • Ch Beziers

    Béziers, 34500, France

  • Ch Cote Basque

    Bayonne, 64109, France

  • Chd Le Mans

    Le Mans, 72000, France

  • Chd Vendee

    La Roche-sur-Yon, 85925, France

  • Chu Amiens

    Amiens, 80054, France

  • Chu Angers

    Angers, 49933, France

  • Chu Creteil

    Créteil, 94000, France

  • Chu Estaing

    Clermont-Ferrand, 63000, France

  • Chu Grenoble

    Grenoble, 38043, France

  • Hopital Huriez

    Lille, 59037, France

  • Hopitaljean Minjoz

    Besançon, 25000, France

  • Hôpital Bretonneau - Hématologie et Thérapie Cellulaire

    Tours, 37044, France

  • Hôpital Privé Sévigné

    Cesson-Sévigné, 35510, France

  • Institut Bergonie

    Bordeaux, 33076, France

  • Institut Paoli Calmette

    Marseille, 130009, France

Conditions

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