New cancer pill enters first human safety tests

NCT ID NCT03264664

Summary

This is the first study in people testing a new oral drug called E7386 for advanced cancers that have stopped responding to standard treatments. Researchers will give the drug to about 60 patients with specific tumor types, including liver cancer, to find the safest and most effective dose. The main goal is to check for side effects and determine how much of the drug the body can tolerate.

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Contacts and locations

Locations

  • California Liver Research Institute

    Pasadena, California, 91105, United States

  • Imperial College Healthcare NHS Trust

    London, W2 1NY, United Kingdom

  • Mayo Clinic Comprehensive Cancer

    Jacksonville, Florida, 32224, United States

  • Mayo Clinic Comprehensive Caner

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic Comprehensive Caner

    Rochester, Minnesota, 55905, United States

  • Royal Free London NHS Foundation Trust, Royal Free Hospital

    London, NW3 2QG, United Kingdom

  • Royal Marsden Hospital NHS Foundation Trust

    Sutton, Surrey, SM2 5PT, United Kingdom

  • The Beatson West of Scotland Cancer Centre

    Glasgow, Lanarkshire, G12 0YN, United Kingdom

  • The Christie NHS Foundation Trust

    Manchester, Lancashire, M20 4BX, United Kingdom

  • USC Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

Conditions

Explore the condition pages connected to this study.