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Gut bacteria supplement tested for Post-Colonoscopy relief

NCT ID NCT07519616

Symptom relief Sponsor: Liaquat University of Medical & Health Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a probiotic called Escherichia coli 5C (Colipral®) can reduce stomach symptoms like bloating and pain after a colonoscopy. About 160 adults will receive either the probiotic or a placebo for 14 days after the procedure. Researchers will track symptom changes using a standard questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Escherichia coli 5C (a probiotic dietary supplement)
What this could lead to
If it works, this could offer a simple, safe way to reduce bloating, pain, and other gut symptoms after a colonoscopy.
What could go wrong
This is a small, early-stage trial with no phase designation. The supplement may work no better than placebo, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 160 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 80 years * Complete diagnostic colonoscopy with achievement of the cecal fundus * Accepted written informed consent for study participation obtained prior to the start of the study Exclusion Criteria: * Chronic inflammatory bowel disease * Complicated Diverticular Disease (DICA \>3) * Suspected or known colorectal malignancy on index colonoscopy * Diagnosed microscopic colitis * Operative colonoscopy * Severe chronic gastrointestinal symptoms judged by the investigator to interfere with the evaluation of study endpoints * Subjects who are immunosuppressed or on systemic immunosuppressive treatment, including patients with primary or acquired immunodeficiency, oncological disease on active treatment with chemotherapy/immunotherapy, or autoimmune diseases on immunosuppressive treatment * Taking probiotics, prebiotics, or synbiotics within 2-4 weeks prior to enrollment * Antibiotic therapy within 4 weeks prior to enrollment * Lack of acceptance of written informed consent

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post-colonoscopy gastrointestinal symptoms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Urbino Carlo Bo, Urbino, Italy

    Urbino, Italy