New drug duo shows promise against stubborn bladder cancer

NCT ID NCT03258593

First seen Jan 06, 2026 · Last updated Apr 28, 2026 · Updated 20 times

Summary

This early-phase study tested whether combining two drugs—durvalumab and vicineum—could safely help people with a high-grade bladder cancer that hadn't spread to muscle but returned after standard BCG treatment. Fifteen adults received the drugs for up to two years. The main goal was to check for side effects, and researchers also looked for signs that the treatment was working.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.