Immunotherapy plus chemoradiation shows promise for inoperable esophageal cancer

NCT ID NCT03777813

First seen Nov 18, 2025 · Last updated Apr 30, 2026 · Updated 17 times

Summary

This study tested whether adding the immunotherapy drug durvalumab to standard chemoradiation helps people with unresectable esophageal cancer. 112 participants received either chemoradiation alone or chemoradiation plus durvalumab, followed by durvalumab maintenance. The main goal was to see if the combination delays cancer growth or improves survival.

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Contacts and locations

Locations

  • CHU Rangueil Larrey

    Toulouse, France

  • Centre Hospitalier Universitaire

    Poitiers, France

  • Centre Oscar Lambret, CLCC UNICANCER

    Lille, France

  • Centre Paul Strauss, CLCC UNICANCER

    Strasbourg, France

  • Hôpital Haut-Lévêque

    Pessac, 33604, France

  • Hôpital Saint Louis, APHP

    Paris, 75010, France

  • Iuct, Clcc Unicancer

    Toulouse, 31059, France

Conditions

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