Could a drug make milk allergy therapy safer and more effective?

NCT ID NCT04148352

First seen Jan 08, 2026 · Last updated May 02, 2026 · Updated 28 times

Summary

This study tested whether adding dupilumab (a drug that reduces allergic inflammation) to milk oral immunotherapy (gradually eating small amounts of milk protein) helps people with cow's milk allergy tolerate more milk with fewer side effects. The trial included 33 people aged 4 to 50 years. The goal was to see if more participants could safely consume at least 2040 mg of milk protein after 18 weeks of treatment. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Mayo Clinic

    Scottsdale, Arizona, 85259, United States

  • Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • Sean N. Parker Center for Allergy & Asthma Research at Stanford University

    Palo Alto, California, 94304, United States

Conditions

Explore the condition pages connected to this study.