Could a drug make milk allergy therapy safer and more effective?

NCT ID NCT04148352

Terminated Disease control Sponsor: Andrew J Long, PharmD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding dupilumab (a drug that reduces allergic reactions) to milk oral immunotherapy (gradually eating small amounts of milk) helps people with cow's milk allergy tolerate more milk with fewer side effects. The trial included 33 people aged 4 to 50 years. The study was stopped early, so results are limited, but the goal was to see if the combination allowed participants to safely consume at least 2040 mg of milk protein.

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Conditions

The condition(s) this trial relates to.

food allergy Heiner syndrome Milk Hypersensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALLERGIES FOOD MILK

Contacts and locations

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Locations

Mayo Clinic

Scottsdale, Arizona, 85259, United States
Phoenix Children's Hospital

Phoenix, Arizona, 85016, United States
Sean N. Parker Center for Allergy & Asthma Research at Stanford University

Palo Alto, California, 94304, United States