Could dupixent help kids with chronic itchy skin disease?

NCT ID NCT06293053

Recruiting now Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests the drug dupilumab (Dupixent) in 18 children aged 6 months to 18 years with prurigo nodularis, a condition causing very itchy skin bumps. The main goals are to measure how the drug moves through the body and to check for side effects. Participants receive injections over 24 weeks and are followed for 16 more weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dupilumab (Dupixent)
What this could lead to: If it works, this could provide a treatment option for children with prurigo nodularis, a chronic itchy skin condition.
What could go wrong: This is a small, early-phase study focused on safety and drug levels, not yet on how well it works. Side effects or lack of effectiveness in kids are possible.

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Conditions

The condition(s) this trial relates to.

prurigo nodularis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRURIGO NODULARIS

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

AXIS Clinicals - Fargo- Site Number : 8400013
RECRUITING

Fargo, North Dakota, 58103, United States
Dell Children's Medical Center- Site Number : 8400007
RECRUITING

Austin, Texas, 78723, United States
Direct Helpers Research Center- Site Number : 8400015
RECRUITING

Hialeah, Florida, 33012, United States
Driscoll Children's Hospital- Site Number : 8400017
RECRUITING

Corpus Christi, Texas, 78411, United States
Life Clinical Trials - Coral Springs- Site Number : 8400018
RECRUITING

Coral Springs, Florida, 33071, United States
MediSearch Clinical Trials- Site Number : 8400004
RECRUITING

Saint Joseph, Missouri, 64506, United States
Mission Dermatology Center- Site Number : 8400011
RECRUITING

Rancho Santa Margarita, California, 92688, United States
Pediatric Center of Excellence (PCE) - Miami Pediatric Endocrinology- Site Number : 8400005
RECRUITING

Coral Gables, Florida, 33146, United States
Stanford University Medical Center CTRU - 800 Welch Road- Site Number : 8400021
RECRUITING

Palo Alto, California, 94304, United States
SunCoast Skin Solutions - Lutz- Site Number : 8400008
RECRUITING

Lutz, Florida, 33558, United States
Tareen Dermatology - Eagan- Site Number : 8400022
RECRUITING

Eagan, Minnesota, 55123, United States
Texas Dermatology and Laser Specialists - San Antonio - Oakwell Court- Site Number : 8400020
RECRUITING

San Antonio, Texas, 78218, United States
USF Health- Site Number : 8400003
RECRUITING

Tampa, Florida, 33606, United States
Vital Prospects Clinical Research Institute - Tulsa- Site Number : 8400002
RECRUITING

Tulsa, Oklahoma, 74136, United States

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