New shot aims to stop uncontrollable skin itch

NCT ID NCT06687967

Ongoing Symptom relief Sponsor: Sanofi Source: ClinicalTrials.gov ↗

Summary

This study is testing if an injectable medication called dupilumab can reduce severe, persistent itch in adults with Lichen Simplex Chronicus (LSC), a skin condition causing thick, itchy patches. About 142 participants will receive either dupilumab or a placebo injection for 24 weeks to see which is better at relieving itch and improving sleep and quality of life. The goal is to find a new treatment option for people whose itch hasn't improved with standard creams.

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Contacts and locations

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Locations

Care Access - Arlington- Site Number : 8400022

Arlington, Virginia, 22206, United States
Center for Clinical Studies - Houston - Binz Street- Site Number : 8400011

Houston, Texas, 77004, United States
Dermatology Research Associates - Los Angeles- Site Number : 8400004

Los Angeles, California, 90045, United States
Equity Medical- Site Number : 8400017

New York, New York, 10023, United States
Investigational Site Number : 0320001

Buenos Aires, 1012, Argentina
Investigational Site Number : 0320002

Mendoza, 5500, Argentina
Investigational Site Number : 0320003

Rosario, Santa Fe Province, 2000, Argentina
Investigational Site Number : 0320004

Buenos Aires, 1061, Argentina
Investigational Site Number : 1240001

London, Ontario, N6H 5L5, Canada
Investigational Site Number : 1240002

Saskatoon, Saskatchewan, S7K 0H6, Canada
Investigational Site Number : 1240005

Edmonton, Alberta, T5K 2V4, Canada
Investigational Site Number : 1240007

Mississauga, Ontario, L5H 1G9, Canada
Investigational Site Number : 1240008

Québec, Quebec, G1W 4R4, Canada
Investigational Site Number : 1240009

Montreal, Quebec, H1Y 3L1, Canada
Investigational Site Number : 1240010

Regina, Saskatchewan, S4V 1R9, Canada
Investigational Site Number : 1520001

Santiago, Reg Metropolitana de Santiago, 7640881, Chile
Investigational Site Number : 1520002

Santiago, Reg Metropolitana de Santiago, 7580206, Chile
Investigational Site Number : 1520003

Santiago, Reg Metropolitana de Santiago, 8420383, Chile
Investigational Site Number : 1560001

Shanghai, 200443, China
Investigational Site Number : 1560002

Beijing, 100191, China
Investigational Site Number : 1560003

Shijiazhuang, 050031, China
Investigational Site Number : 1560004

Hangzhou, 310014, China
Investigational Site Number : 1560005

Suzhou, 215006, China
Investigational Site Number : 1580001

Taipei, 100, Taiwan
Investigational Site Number : 1580002

Kaohsiung City, 833, Taiwan
Investigational Site Number : 1580003

New Taipei City, 235, Taiwan
Investigational Site Number : 2030001

Ostrava, 702 00, Czechia
Investigational Site Number : 2760001

Magdeburg, 39104, Germany
Investigational Site Number : 2760003

Bad Bentheim, 48455, Germany
Investigational Site Number : 3000001

Athens, 124 62, Greece
Investigational Site Number : 3000002

Thessaloniki, 546 42, Greece
Investigational Site Number : 3000003

Thessaloniki, 564 29, Greece
Investigational Site Number : 3480001

Debrecen, 4032, Hungary
Investigational Site Number : 3480002

Kaposvár, 7400, Hungary
Investigational Site Number : 3800001

Rome, Roma, 00133, Italy
Investigational Site Number : 3800002

Bologna, 40138, Italy
Investigational Site Number : 3920001

Kamiamakusa, Kumamoto, 861-3106, Japan
Investigational Site Number : 3920002

Ebina-shi, Kanagawa, 243-0432, Japan
Investigational Site Number : 3920003

Tachikawa, Tokyo, 190-0023, Japan
Investigational Site Number : 3920005

Kagoshima, 890-0063, Japan
Investigational Site Number : 3920007

Sakai, Osaka, 593-8324, Japan
Investigational Site Number : 3920009

Fukuoka, 819-0167, Japan
Investigational Site Number : 4840001

Chihuahua City, 31000, Mexico
Investigational Site Number : 4840003

Aguascalientes, 20127, Mexico
Investigational Site Number : 6200001

Porto, 4099-001, Portugal
Investigational Site Number : 6200002

Coimbra, 3000-075, Portugal
Investigational Site Number : 6200003

Lisbon, 1998-018, Portugal
Investigational Site Number : 7240002

Barcelona, Catalunya [Cataluña], 08041, Spain
Investigational Site Number : 7240003

Barcelona, Barcelona [Barcelona], 08035, Spain
Investigational Site Number : 7240004

Valencia, 46015, Spain
Investigational Site Number : 7240005

Barcelona, Catalunya [Cataluña], 08036, Spain
Investigational Site Number : 7920001

Samsun, 55139, Turkey (Türkiye)
Investigational Site Number : 7920002

Istanbul, 34662, Turkey (Türkiye)
Investigational Site Number : 7920003

Adapazarı, 54100, Turkey (Türkiye)
Investigational Site Number : 8260001

London, England, E1 1BB, United Kingdom
Investigational Site Number : 8260002

Milton Keynes, Buckinghamshire, MK19 6FG, United Kingdom
JDR Dermatology Research- Site Number : 8400023

Las Vegas, Nevada, 89145, United States
MedCare Pharma - Houston - Cypress Creek Parkway- Site Number : 8400014

Houston, Texas, 77090, United States
Michigan Center for Research Company- Site Number : 8400013

Clarkston, Michigan, 48346, United States
Onsite Clinical Solutions - Huntersville- Site Number : 8400033

Huntersville, North Carolina, 28078, United States
Quality Care Clinical Research- Site Number : 8400034

Miami, Florida, 33142, United States
Red River Research Partners - Fargo- Site Number : 8400007

Fargo, North Dakota, 58103, United States
Wake Forest University Health Sciences- Site Number : 8400028

Winston-Salem, North Carolina, 27104, United States

Conditions

Explore the condition pages connected to this study.

LICHEN SIMPLEX CHRONICUS