Eczema itch study reveals nerve changes with dupilumab

NCT ID NCT04823130

First seen Oct 31, 2025 · Last updated May 06, 2026 · Updated 19 times

Summary

This study looked at how dupilumab, a treatment for moderate-to-severe eczema, changes nerve fibers in the skin and reduces itching. 54 adults with chronic itch took part. Researchers took skin samples to measure nerve density and branching before and after treatment. The goal was to understand how the drug eases itch.

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Contacts and locations

Locations

  • Investigational Site Number 2760001

    Münster, 48149, Germany

  • Investigational Site Number 8400001

    Miami, Florida, 33136, United States

  • Investigational Site Number 8400002

    East Windsor, New Jersey, 08520, United States

Conditions

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