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New hope for kids with severe eczema: drug combo shows promise in japanese trial

NCT ID NCT04678882

Completed Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This study tested whether adding dupilumab (an injectable drug) to standard steroid creams can better control eczema in Japanese children aged 6 months to 18 years whose eczema was not helped by existing treatments. The trial involved 62 participants and lasted 16 weeks. The main goal was to see if the combination improved skin symptoms by at least 75% compared to steroids alone.

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Contacts and locations

Locations

  • Investigational Site Number : 3920001

    Hiroshima, Hiroshima, 734-8551, Japan

  • Investigational Site Number : 3920003

    Sagamihara-shi, Kanagawa, 252-0392, Japan

  • Investigational Site Number : 3920006

    Tsu, Mie-ken, 514-0125, Japan

  • Investigational Site Number : 3920007

    Kobe, Hyōgo, 658-0082, Japan

  • Investigational Site Number : 3920008

    Kobe, Hyōgo, 653-0836, Japan

  • Investigational Site Number : 3920009

    Sapporo, Hokkaido, 060-0807, Japan

  • Investigational Site Number : 3920010

    Yokohama, Kanagawa, 225-0015, Japan

  • Investigational Site Number : 3920011

    Nagoya, Aichi-ken, 457-8510, Japan

  • Investigational Site Number : 3920012

    Koto-ku, Tokyo, 136-0074, Japan

  • Investigational Site Number : 3920013

    Sapporo, Hokkaido, 004-0063, Japan

  • Investigational Site Number : 3920014

    Toyoake-shi, Aichi-ken, 470-1192, Japan

  • Investigational Site Number : 3920015

    Fukutsu-shi, Fukuoka, 811-3217, Japan

  • Investigational Site Number : 3920016

    Kumagaya-shi, Saitama, 360-0018, Japan

  • Investigational Site Number : 3920017

    Yokohama, Kanagawa, 221-0825, Japan

  • Investigational Site Number : 3920019

    Toyonaka-shi, Osaka, 560-0085, Japan

  • Investigational Site Number : 3920020

    Sakai-shi, Osaka, 593-8324, Japan

  • Investigational Site Number : 3920021

    Habikino-shi, 583-8588, Japan

  • Investigational Site Number : 3920022

    Toshima-ku, Tokyo, 170-0002, Japan

  • Investigational Site Number : 3920023

    Chuo-ku, Tokyo, 104-0031, Japan

Conditions

Explore the condition pages connected to this study.

ATOPIC DERMATITIS