New drug trial targets debilitating fungal sinus disease

NCT ID NCT04684524

Completed Disease control Sponsor: Sanofi Source: ClinicalTrials.gov ↗

Summary

This study tested whether the drug dupilumab could help control allergic fungal rhinosinusitis (AFRS), a severe sinus condition. It involved 62 adults and adolescents with confirmed AFRS who received either dupilumab or a placebo for a year. The main goal was to see if the drug could reduce sinus blockage seen on CT scans and improve symptoms like congestion and loss of smell.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Advanced ENT and Allergy Site Number : 8400004

Louisville, Kentucky, 40220, United States
Alamo ENT Associates Site Number : 8400018

San Antonio, Texas, 78258, United States
Asthma Allergy & Immunology Clinical Research Unit Site Number : 8400001

Tampa, Florida, 33613, United States
Eastern Virginia Medical School (EVMS) Medical Group - Otola Site Number : 8400008

Norfolk, Virginia, 23507, United States
Emory University Hospital Midtown Campus Site Number : 8400009

Atlanta, Georgia, 30308, United States
Investigational Site Number : 0320001

CABA, Buenos Aires, C1425BEN, Argentina
Investigational Site Number : 0320002

Buenos Aires, C1121ABE, Argentina
Investigational Site Number : 0320003

CABA, Buenos Aires, C1414AIF, Argentina
Investigational Site Number : 0320004

Mendoza, 5500, Argentina
Investigational Site Number : 0320005

Rosario, Santa Fe Province, 2000, Argentina
Investigational Site Number : 1240001

Vancouver, British Columbia, V6Z 1Y6, Canada
Investigational Site Number : 1560001

Beijing, 100730, China
Investigational Site Number : 1560002

Nanjing, 210029, China
Investigational Site Number : 1560003

Chengdu, 610041, China
Investigational Site Number : 1560004

Changsha, 410013, China
Investigational Site Number : 1560005

Beijing, 100050, China
Investigational Site Number : 1560006

Hangzhou, 310003, China
Investigational Site Number : 1560008

Taiyuan, 030001, China
Investigational Site Number : 1560009

Shanghai, 200030, China
Investigational Site Number : 1560011

Qingdao, 266555, China
Investigational Site Number : 1560012

Hefei, China
Investigational Site Number : 1560013

Fuzhou, 350005, China
Investigational Site Number : 3560003

Coimbatore, 641028, India
Investigational Site Number : 3560006

Jodhpur, 342005, India
Investigational Site Number : 3560008

New Delhi, 110 062., India
Investigational Site Number : 3760001

Petah Tikva, 49100, Israel
Investigational Site Number : 3760002

Rehovot, 76100, Israel
Investigational Site Number : 3920001

Meguro-ku, Tokyo, 153-8515, Japan
Investigational Site Number : 3920003

Shinagawa-ku, Tokyo, 141-0001, Japan
Investigational Site Number : 3920006

Shizuoka, Shizuoka, 420-0853, Japan
Investigational Site Number : 3920008

Bunkyo-ku, Tokyo, 113-8431, Japan
Investigational Site Number : 3920009

Shinjuku-ku, Tokyo, 160-8582, Japan
Investigational Site Number : 3920010

Isehara, Kanagawa, 2591193, Japan
Investigational Site Number : 6820001

Riyadh, 22252, Saudi Arabia
Investigational Site Number : 6820002

Riyadh, 12713, Saudi Arabia
Investigational Site Number : 7920001

Istanbul, 34093, Turkey (Türkiye)
Investigational Site Number : 7920003

Izmir, 35340, Turkey (Türkiye)
Investigational Site Number : 7920004

Adana, 01380, Turkey (Türkiye)
Investigational Site Number : 7920005

Malatya, 44280, Turkey (Türkiye)
Investigational Site Number : 7920006

Izmir, 35100, Turkey (Türkiye)
Investigational Site Number : 7920007

Istanbul, 34865, Turkey (Türkiye)
National Allergy and Asthma Research, LLC Site Number : 8400002

Charleston, South Carolina, 29407, United States
REX Clinical Trials Site Number : 8400017

Beaumont, Texas, 77701-3713, United States
South Louisiana Ear, Nose, Throat and Facial Plastic Surgery Site Number : 8400019

Mandeville, Louisiana, 70471, United States
USA Clinical Trials Site Number : 8400020

San Antonio, Texas, 78229, United States
Ut- Houston Medical School Site Number : 8400010

Houston, Texas, 77030, United States
Vanderbilt University Medical Center Site Number : 8400013

Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.

ALLERGIC FUNGAL RHINOSINUSITIS