New drug cocktail aims to revive immunotherapy in tough lung cancers

NCT ID NCT05013450

First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 19 times

Summary

This early-stage trial tests whether adding two anti-inflammatory drugs (dupilumab and anakinra) to standard immunotherapy can help shrink tumors in people with advanced non-small cell lung cancer that has stopped responding to prior immunotherapy. About 33 adults will receive the combination to check safety and see if tumors respond. The goal is to overcome resistance to current treatments, not to cure the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Tisch Cancer Institute, Mount Sinai Hospital

    New York, New York, 10003, United States

Conditions

Explore the condition pages connected to this study.