New hope for advanced cancers: DSB2455 enters human trials
NCT ID NCT06458712
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 24 times
Summary
This early-phase trial tests a new drug called DSB2455 in adults with advanced cancers that have a specific DNA repair problem. The main goals are to find a safe dose and see if the drug can shrink tumors. About 90 participants will take part in this study across multiple centers.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital 12 de Octubre
RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitari Vall d'Hebron
RECRUITINGBarcelona, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Reina Sofía
RECRUITINGCórdoba, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Virgen de la Victoria
RECRUITINGMálaga, 29010, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Bergonie
RECRUITINGBordeaux, 33000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Godinot
RECRUITINGReims, 51100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Instituto Valenciano de Oncologia
RECRUITINGValencia, 46009, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START Barcelona, CIOCC, Hospital Universitario Nou Delfos
RECRUITINGBarcelona, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START La Rioja, Hospital Universitario San Pedro
RECRUITINGLogroño, La Rioja, 26006, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START Madrid-CIOCC, Hospital Universitario HM Sanchinarro
RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Texas M. D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitary Hospital Virgen del Rocio
RECRUITINGSeville, 41013, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale Cancer Center - Yale New Haven Hospital
RECRUITINGNew Haven, Connecticut, 06520, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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