New drug DSB2455 targets Hard-to-Treat cancers in early trial
NCT ID NCT06458712
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new drug called DSB2455 in adults with advanced cancers (breast, ovarian, prostate, pancreatic, or brain metastases) that have a specific DNA repair problem. The main goals are to check safety and see if the drug shrinks tumors. About 180 participants will receive the drug in increasing doses to find the best dose with manageable side effects.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hospital 12 de Octubre
RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitari Vall d'Hebron
RECRUITINGBarcelona, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Reina Sofía
RECRUITINGCórdoba, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital Universitario Virgen de la Victoria
RECRUITINGMálaga, 29010, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Bergonie
RECRUITINGBordeaux, 33000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Godinot
RECRUITINGReims, 51100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Instituto Valenciano de Oncologia
RECRUITINGValencia, 46009, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Orszagos Onkologiai Intezet
RECRUITINGBudapest, 1122, Hungary
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START Barcelona, CIOCC, Hospital Universitario Nou Delfos
RECRUITINGBarcelona, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START La Rioja, Hospital Universitario San Pedro
RECRUITINGLogroño, La Rioja, 26006, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START Madrid-CIOCC, Hospital Universitario HM Sanchinarro
RECRUITINGMadrid, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Texas M. D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tisch Cancer Institute Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universitary Hospital Virgen del Rocio
RECRUITINGSeville, 41013, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Yale Cancer Center - Yale New Haven Hospital
RECRUITINGNew Haven, Connecticut, 06520, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••