New hope for lymphoma patients: experimental drug DS-3201b enters human testing

NCT ID NCT02732275

First seen May 09, 2026 · Last updated May 13, 2026 · Updated 1 time

Summary

This early-phase study tests an experimental drug called DS-3201b in adults with non-Hodgkin lymphoma whose cancer has returned or stopped responding to standard treatments. The main goals are to find a safe dose and see how well the drug works. About 100 participants will take part in three parts: dose finding, effectiveness testing, and checking how the drug interacts with other medicines.

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Contacts and locations

Locations

  • City of Hope National Medical center

    Duarte, California, 91010, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Imamura General Hospital

    Kagoshima, Kagoshima-ken, 890-0064, Japan

  • Iwate Medical University Hospital

    Morioka, Iwate, 020-8505, Japan

  • Kagoshima University Hospital

    Kagoshima, Kagoshima-ken, 890-8520, Japan

  • Kumamoto University Hosipital

    Kumamoto, Kumamoto, 860-8556, Japan

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Nagasaki University Hospital

    Nagasaki, Nagasaki, 852-8501, Japan

  • Nagoya City University Hospital

    Nagoya, Aichi-ken, 467-8602, Japan

  • National Cancer Center Hospital

    Chūōku, Toyko, 104-0045, Japan

  • National Cancer Center Hospital East

    Kahiwa-shi, Chiba, 277-8577, Japan

  • The Institute of Medical Science, The University of Tokyo

    Minato-ku, Tokyo, 108-8639, Japan

  • The Ohio State University Wexner Medical Center and James Cancer Hospital

    Columbus, Ohio, 43210, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of the Ryukyus Hospital

    Nakagami-gun, Okinawa, 903-0215, Japan

  • Weill Cornell Medicine

    New York, New York, 10021, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

Conditions

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