New injection could halt leading cause of blindness in seniors

NCT ID NCT06373731

Summary

This late-stage clinical trial is testing whether daily injections of an experimental drug called elamipretide can slow the progression of dry age-related macular degeneration (AMD), a leading cause of vision loss in older adults. The study involves 313 participants who will receive either the active drug or a placebo injection for 96 weeks. Researchers will measure whether the treatment reduces the rate of photoreceptor loss in the retina and helps preserve vision.

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Contacts and locations

Locations

  • Associated Retina Consultants

    Phoenix, Arizona, 85020, United States

  • Associated Vitreoretinal and Uveitis Consultants

    Carmel, Indiana, 46290, United States

  • Augenzentrum am St. Franziskus-Hospital

    Münster, Germany

  • Austin Clinical Research, LLC

    Austin, Texas, 78750, United States

  • Axon Clinical, s.r.o.

    Prague, Czechia

  • Barnet Dulaney Perkins Eye Center

    Sun City, Arizona, 85351, United States

  • Bay Area Retina Associates

    Walnut Creek, California, 94598, United States

  • Capital Eye Specialists

    Wellington, 6011, New Zealand

  • Centro de Oftalmologia Barraquer

    Barcelona, Spain

  • Connecticut Eye Consultants, P.C.

    Danbury, Connecticut, 06810, United States

  • Department für Augenheilkunde

    Tübingen, Germany

  • Department of Ophthalmology, Azienda SanitariaUniversitaria Friuli Centrale

    Udine, Italy

  • Emerson Clinical Research Institute

    Falls Church, Virginia, 22042, United States

  • Florida Retina Institute

    Orlando, Florida, 32806, United States

  • Fondazione Policlinico Gemelli

    Roma, Italy

  • Fundacion Aiken de la Comunitat Valenciana

    Valencia, Spain

  • Ganglion Medical Center

    Pécs, Hungary

  • Hospital Luigi Sacco Ophthalmology Dept

    Milan, Italy

  • IRRCS Ospendale San Raffaele

    Milan, Italy

  • Kellogg Eye Center

    Ann Arbor, Michigan, 48105, United States

  • Klinik und Poliklinik für Augenheilkunde- Universitätsklinik Regensburg

    Regensburg, Germany

  • Macular Services, Central Middlesex Hospital, NHS Foundation Trust

    London, United Kingdom

  • Medical Center Ophthalmology Associates

    San Antonio, Texas, 78240, United States

  • Mid Atlantic Retina

    Cherry Hill, New Jersey, 08034, United States

  • Mid Atlantic Retina Specialist

    Hagerstown, Maryland, 21740, United States

  • NJ Retina

    Teaneck, New Jersey, 07666, United States

  • OMIQ Research

    Barcelona, Spain

  • Oftalvist

    Valencia, Spain

  • Ophthalmic Consultants of Boston

    Boston, Massachusetts, 02114, United States

  • Orange County Retinal Medical Group

    Santa Ana, California, 92705, United States

  • Pacific Northwest Retina, PLLC

    Silverdale, Washington, 98383, United States

  • Policlinico Milano

    Milan, Italy

  • Retina Associates of Southern California

    Huntington Beach, California, 92607, United States

  • Retina Consultants of Minnesota

    Minneapolis, Minnesota, 55435, United States

  • Retina Consultants of San Diego

    Poway, California, 92064, United States

  • Retina Consultants of Southern Colorado

    Colorado Springs, Colorado, 80909, United States

  • Retina Consultants of Texas

    Bellaire, Texas, 77401, United States

  • Retina Consultants of Texas

    The Woodlands, Texas, 77384, United States

  • Retina Northwest, PC

    Portland, Oregon, 97221, United States

  • Retina Research Institute of Texas

    Abilene, Texas, 79606, United States

  • Retina Vitreous Associates of Florida

    St. Petersburg, Florida, 33711, United States

  • Retina Vitreous Center

    Edmond, Oklahoma, 73013, United States

  • Retinal Consultants Medical Group

    Sacramento, California, 95825, United States

  • South Tyneside and Sunderland NHS Foundation Trust - Sunderland Eye Infirmary

    Sunderland, United Kingdom

  • Southern Eye Specialists

    Christchurch, 8013, New Zealand

  • Texas Retina Associates of Plano

    Plano, Texas, 75075, United States

  • University Hospitals Bristol NHS Foundation Trust - Bristol Eye Hospital

    Bristol, United Kingdom

  • University Hospitals of Leicester, Leicester Royal Infirmary

    Leicester, United Kingdom

  • University Of Debrecen Eye Center

    Debrecen, Hungary

  • University Retina and Macula Associates

    Oak Forest, Illinois, 60452, United States

  • University of Szeged, Department of Ophthalmology

    Szeged, Hungary

  • Valley Retina Institute

    McAllen, Texas, 78503, United States

  • Vitreo Retinal Associates

    Gainesville, Florida, 32607, United States

Conditions

Explore the condition pages connected to this study.