Healthy volunteers needed to uncover genetic drug interactions

NCT ID NCT05789173

First seen Feb 23, 2026 · Last updated May 08, 2026 · Updated 10 times

Summary

This study looks at how a person's genes and the HIV drug efavirenz change the way the body processes methadone and tizanidine. Sixty healthy volunteers, grouped by their CYP2B6 gene type, will take these drugs with and without efavirenz. The goal is to understand drug interactions, not to treat any disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University School of Medicine

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.