New drug targets Hard-to-Treat lung cancer mutations

NCT ID NCT07249372

First seen Jan 09, 2026 · Last updated May 25, 2026 · Updated 15 times

Summary

This study tests a new drug called DRP-104 in people with advanced non-small cell lung cancer that has specific genetic changes (NFE2L2 or KEAP1). The drug works by blocking glutamine, a nutrient cancer cells need to grow. About 37 participants will receive the drug to see if it shrinks tumors or slows cancer progression. This is for patients whose cancer has worsened after standard treatments like chemotherapy and immunotherapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University

    RECRUITING

    New York, New York, 10032, United States

    Contact

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

Conditions

Explore the condition pages connected to this study.