New hope for women with recurrent pregnancy failure: Antibiotic-Hormone combo shows promise

NCT ID NCT07488949

First seen Mar 23, 2026 · Last updated Jun 12, 2026 · Updated 11 times

Summary

This study looks at whether adding a hormone medication (medroxyprogesterone acetate) to standard antibiotic treatment (doxycycline) can better treat chronic endometritis—a womb infection linked to repeated pregnancy loss. About 1,000 women aged 20-45 with this condition will be randomly assigned to one of two treatment groups. The main goal is to see which approach leads to higher cure rates and better pregnancy outcomes, including live births.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lanzhou University Second Hospital

    RECRUITING

    Lanzhou, Gansu, 730030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

chronic endometritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.