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Could a single daily moisturizer tame ichthyosis skin?

NCT ID NCT07783165

Symptom relief Sponsor: Dermal Laboratories Ltd Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 24, 2026 · Last updated Sep 09, 2026 · Updated 3 times

Summary

This study asks whether a once-daily emollient called Doublebase Once can safely help manage ichthyosis, a condition causing dry, scaly skin. About 100 people with ichthyosis will replace their usual moisturizer with Doublebase Once for 28 days, applying it once daily. Participants answer questionnaires about their skin condition and product use to see how well it performs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Doublebase Once, a leave-on emollient (moisturizer) applied once daily
What this could lead to
If successful, this could support Doublebase Once as a convenient once-daily option to help manage dry, scaly skin in people with ichthyosis.
What could go wrong
This is a short, non-comparative survey, not a controlled trial, so results may be subjective and not prove effectiveness beyond usual emollient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with ichthyosis of any severity previously diagnosed by a Healthcare Professional (HCP). * Patients normally managing their skin condition by regular and ongoing use of leave-on emollient(s). * Patients willing to use Doublebase Once for one month, instead of the patients usual emollient, as part of their normal ichthyosis management for the area(s) they have selected to treat for the study? This would also involve trying to use it once daily only Exclusion Criteria: * Does not regularly use an emollient * Known history of intolerance or skin sensitivity to any of the ingredients of Doublebase Once (as identified on the Patient Information Sheet and product labelling), or similar products used. * Currently participating in a study involving an investigational medicinal product/medical device or having participated in the previous 30 days. * Patients currently residing in Northern Ireland (this is due to the different approval process). * Patients (or their parents/legal guardians, in the case of infants, very young children or adolescent adults) who may have difficulties completing the feedback questionnaires, which will be written in English only. * Employees of the Sponsor (Dermal or the Diomed group companies), or any immediate family member (partner, offspring, parents, siblings or sibling's offspring) of such employees

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Conditions

The condition(s) this trial relates to.

ichthyosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ichthyosis

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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