One-Time infusion aims to halt devastating muscle disease in toddlers

NCT ID NCT05429372

Summary

This study tested a one-time gene therapy in boys aged 2 to 4 with Duchenne muscular dystrophy (DMD). The main goals were to check if the treatment was safe and to see if it could help their muscles produce a crucial protein called dystrophin. The trial was small, with 10 participants, and has been terminated.

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Contacts and locations

Locations

  • CTSI Clinical Research Center

    Salt Lake City, Utah, 84108, United States

  • Perth Children's Hospital

    Nedlands, Western Australia, 6009, Australia

  • Primary Children's Hospital

    Salt Lake City, Utah, 84113, United States

  • The Children's Hospital at Westmead

    Westmead, New South Wales, 2145, Australia

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19146, United States

  • The Royal Children's Hospital Melbourne

    Parkville, Victoria, 3052, Australia

  • UF Health Shands Hospital

    Gainesville, Florida, 32610, United States

  • University of Florida

    Gainesville, Florida, 32610, United States

  • University of Utah Clinical Neurosciences Center

    Salt Lake City, Utah, 84132, United States

  • University of Utah Hospital

    Salt Lake City, Utah, 84132, United States

  • University of Utah Hospital & Clinics Investigational Drug Services

    Salt Lake City, Utah, 84112, United States

  • University of Utah Imaging and Neurosciences Center

    Salt Lake City, Utah, 84108, United States

Conditions

Explore the condition pages connected to this study.