New hope for Alzheimer's? phase 3 trial of DMB-I begins
NCT ID NCT07251023
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the drug DMB-I (latrepirdine) can improve thinking and memory in people with mild to moderate Alzheimer's dementia. About 450 adults aged 60-90 will take either DMB-I, a placebo, or an active comparator for 26 weeks. Researchers will compare changes in cognitive test scores and monitor for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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"Medical Center Nova Vita" LLC
RECRUITINGRostov-on-Don, 344082, Russia
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"Medical services" LLC
RECRUITINGSaint Petersburg, 194356, Russia
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"Sphera Med" LLC
RECRUITINGSaint Petersburg, 197342, Russia
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Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
RECRUITINGMoscow, 119991, Russia
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Federal State Budgetary Institution "Federal Center for Brain and Neurotechnology" of the Federal Medical and Biological Agency
RECRUITINGMoscow, 117513, Russia
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Moscow State budgetary healthcare institution "City Clinical Hospital named after V.M. Buyanov of the Moscow Healthcare Department"
RECRUITINGMoscow, 115516, Russia
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Nizhny Novgorod region State budgetary healthcare institution " Nizhny Novgorod Clinical Psychiatric Hospital No. 1"
RECRUITINGNizhny Novgorod, 603155, Russia
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Saint Petersburg State budgetary healthcare institution "City Hospital No. 40 of Kurortniy district"
RECRUITINGSaint Petersburg, 197706, Russia
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Saint Petersburg State budgetary healthcare institution "Psychiatric Hospital No. 1 named after P.P. Kashchenko"
RECRUITINGSaint Petersburg, 188357, Russia
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Saint Petersburg State budgetary healthcare institution "Psychoneurologic dispensary № 5"
RECRUITINGSaint Petersburg, 195176, Russia
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State autonomous healthcare institution "Transregional Clinical Diagnostic Center"
RECRUITINGKazan', 420101, Russia
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State budgetary healthcare institution "Leningrad Regional Mental Health Center"
RECRUITINGRoshchino, 188820, Russia