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New hope for Alzheimer's? phase 3 trial of DMB-I begins

NCT ID NCT07251023

Recruiting now Disease control Sponsor: Bigespas LTD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug DMB-I (latrepirdine) can improve thinking and memory in people with mild to moderate Alzheimer's dementia. About 450 adults aged 60-90 will take either DMB-I, a placebo, or an active comparator for 26 weeks. Researchers will compare changes in cognitive test scores and monitor for side effects.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALZHEIMER TYPE DEMENTIA

Contacts and locations

Locations

  • "Medical Center Nova Vita" LLC

    RECRUITING

    Rostov-on-Don, 344082, Russia

  • "Medical services" LLC

    RECRUITING

    Saint Petersburg, 194356, Russia

  • "Sphera Med" LLC

    RECRUITING

    Saint Petersburg, 197342, Russia

  • Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

    RECRUITING

    Moscow, 119991, Russia

  • Federal State Budgetary Institution "Federal Center for Brain and Neurotechnology" of the Federal Medical and Biological Agency

    RECRUITING

    Moscow, 117513, Russia

  • Moscow State budgetary healthcare institution "City Clinical Hospital named after V.M. Buyanov of the Moscow Healthcare Department"

    RECRUITING

    Moscow, 115516, Russia

  • Nizhny Novgorod region State budgetary healthcare institution " Nizhny Novgorod Clinical Psychiatric Hospital No. 1"

    RECRUITING

    Nizhny Novgorod, 603155, Russia

  • Saint Petersburg State budgetary healthcare institution "City Hospital No. 40 of Kurortniy district"

    RECRUITING

    Saint Petersburg, 197706, Russia

  • Saint Petersburg State budgetary healthcare institution "Psychiatric Hospital No. 1 named after P.P. Kashchenko"

    RECRUITING

    Saint Petersburg, 188357, Russia

  • Saint Petersburg State budgetary healthcare institution "Psychoneurologic dispensary № 5"

    RECRUITING

    Saint Petersburg, 195176, Russia

  • State autonomous healthcare institution "Transregional Clinical Diagnostic Center"

    RECRUITING

    Kazan', 420101, Russia

  • State budgetary healthcare institution "Leningrad Regional Mental Health Center"

    RECRUITING

    Roshchino, 188820, Russia

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