Could skipping a breathing test speed up ventilator removal?
NCT ID NCT07019636
First seen Jul 17, 2026 · Last updated Jul 17, 2026
Summary
This study tests whether patients who are ready to come off a breathing machine can be safely extubated right away, without first doing a spontaneous breathing trial. It includes adults aged 18–65 who have been on a ventilator for 1–4 days and are considered low risk for extubation failure. The main goal is to see if direct extubation leads to more patients staying off the ventilator for at least 72 hours compared to the standard approach of a breathing test first.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could simplify weaning protocols for low-risk patients, reducing time on ventilators and hospital stays.
- What could go wrong
- This is a single, open-label trial with 314 participants, so results may not apply broadly. Direct extubation could increase the risk of breathing failure or need for reintubation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for WEANING FROM MECHANICAL VENTILATION, EXTUBATION are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Hôpital Pitié Salpêtrière
RECRUITINGParis, 75013, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.