New filler takes on wrinkle rival in Head-to-Head trial

NCT ID NCT07412392

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares a new injectable filler (DIOSHA S Lido) with an existing one (YOUTHFILL) for temporarily softening moderate to deep smile lines. About 60 adults aged 19 to 75 with symmetrical wrinkles will receive both treatments in a blinded, matched-pairs design. The main goal is to see if the new filler works as well as the current option over 24 weeks.

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