New filler faces off against popular wrinkle treatment

NCT ID NCT07412392

First seen Feb 18, 2026 · Last updated May 03, 2026 · Updated 13 times

Summary

This study compares a new injectable filler (DIOSHA S Lido) with an existing one (YOUTHFILL) for temporarily softening moderate to deep smile lines (nasolabial folds). About 60 adults aged 19 to 75 with symmetrical wrinkles will receive both treatments in a blinded, matched-pairs design. The goal is to see if the new filler works as well and is as safe as the current option.

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