New drug could scratch the itch for dialysis patients

NCT ID NCT07526324

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether the drug difelikefalin can reduce severe itching in people with chronic kidney disease who are on hemodialysis. About 106 adults will receive either the drug or a placebo after each dialysis session for 6 weeks. The main goal is to see if itching scores improve, with a focus on safety and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Difelikefalin injection
What this could lead to
If it works, this could provide a new option to relieve severe itching in people on dialysis, improving their quality of life.
What could go wrong
This is a small, early-stage trial with only 106 participants. The drug may not prove more effective than placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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