New ointment could ease blistering in rare skin disease

NCT ID NCT06073132

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an ointment called diacerein 1% on people with a rare genetic skin condition (EBS) that causes fragile skin and painful blisters. About 80 participants will apply the ointment daily to see if it clears blisters and reduces pain. The trial is double-blind, meaning neither patients nor doctors know who gets the real ointment versus a placebo.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asian Hospital

    City of Muntinlupa, Philippines

  • Children's Health Ireland

    Dublin, Ireland

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Cincinnati Childrens Hospital

    Cincinnati, Ohio, 45229, United States

  • Dermatology Hospital of Southern Medical University

    Guangzhou, Guangdong, China

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano

    Milan, Italy

  • Gangnam Severane Hospital

    Seoul, South Korea

  • Great Ormond Street Hospital (GOSH) for Children NHS Foundation Trust - Somers Clinical Research Facility (CRF)

    London, United Kingdom

  • Health Cube Medical Clinics

    Mandaluyong, Philippines

  • Hospital Tunku Azizah (Hospital Wanita Dan Kanak-kanak Kuala Lumpur)

    Kuala Lumpur, Malaysia

  • Hospital Universitario La Paz

    Madrid, Spain

  • Hospital of Skin and Venereal Diseases of Thessaloniki

    Thessaloniki, Greece

  • Iloilo Doctors Hospital

    Iloilo City, Philippines

  • Istituto Dermopatico dell'Immacolata (IDI) - Istituto di

    Rome, Italy

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Mission dermatology Center

    Rancho Santa Margarita, California, 92688, United States

  • National Cheng Kung University Hospital

    Tainan, Taiwan

  • Northwestern University - Lurie Childrens's Hospital

    Chicago, Illinois, 60611, United States

  • OT.CO Clinic Osipowicz & Turkowski

    Warsaw, Poland

  • Postgraduate Institute of Medical Education and Research (PGIMER)

    Chandigarh, India

  • Premier Specialists

    Kogarah, Australia

  • Sheikh Khalifa Medical City (SKMC)

    Abu Dhabi, United Arab Emirates

  • Stanford University

    Stanford, California, 94304, United States

  • Sydney Children's Hospital

    Randwick, Australia

  • Tel Aviv Sourasky Medical Center

    Tel Aviv, Israel

  • Texas Dermatology and Laser Specialists

    San Antonio, Texas, 78218, United States

  • UOS "Centro delle Dermatosi Croniche Complesse e Genodermatosi" UOC Dermatologia

    Rome, Italy

  • UZ Leuven

    Leuven, Belgium

  • Universitaetsklinik fuer Dermatologie und Allergologie

    Salzburg, Austria

  • Università degli Studi di Modena e Reggio Emilia (UNIMORE)

    Modena, Italy