New ointment could ease painful blisters for kids and adults with rare skin disease
NCT ID NCT06073132
First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 32 times
Summary
This study tests an ointment called diacerein 1% for people with a rare genetic skin condition called generalized epidermolysis bullosa simplex (EBS), which causes fragile skin and painful blisters. About 80 participants aged 6 months and older will receive either the ointment or a placebo for several weeks, and then all may receive the active ointment in an open-label extension. The goal is to see if the ointment reduces blistering and pain.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Asian Hospital
City of Muntinlupa, Philippines
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Children's Health Ireland
Dublin, Ireland
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Cincinnati Childrens Hospital
Cincinnati, Ohio, 45229, United States
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Dermatology Hospital of Southern Medical University
Guangzhou, Guangdong, China
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano
Milan, Italy
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Gangnam Severane Hospital
Seoul, South Korea
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Great Ormond Street Hospital (GOSH) for Children NHS Foundation Trust - Somers Clinical Research Facility (CRF)
London, United Kingdom
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Health Cube Medical Clinics
Mandaluyong, Philippines
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Hospital Tunku Azizah (Hospital Wanita Dan Kanak-kanak Kuala Lumpur)
Kuala Lumpur, Malaysia
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Hospital Universitario La Paz
Madrid, Spain
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Hospital of Skin and Venereal Diseases of Thessaloniki
Thessaloniki, Greece
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Iloilo Doctors Hospital
Iloilo City, Philippines
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Istituto Dermopatico dell'Immacolata (IDI) - Istituto di
Rome, Italy
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Mission dermatology Center
Rancho Santa Margarita, California, 92688, United States
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National Cheng Kung University Hospital
Tainan, Taiwan
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Northwestern University - Lurie Childrens's Hospital
Chicago, Illinois, 60611, United States
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OT.CO Clinic Osipowicz & Turkowski
Warsaw, Poland
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Postgraduate Institute of Medical Education and Research (PGIMER)
Chandigarh, India
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Premier Specialists
Kogarah, Australia
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Sheikh Khalifa Medical City (SKMC)
Abu Dhabi, United Arab Emirates
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Stanford University
Stanford, California, 94304, United States
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Sydney Children's Hospital
Randwick, Australia
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Tel Aviv Sourasky Medical Center
Tel Aviv, Israel
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Texas Dermatology and Laser Specialists
San Antonio, Texas, 78218, United States
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UOS "Centro delle Dermatosi Croniche Complesse e Genodermatosi" UOC Dermatologia
Rome, Italy
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UZ Leuven
Leuven, Belgium
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Universitaetsklinik fuer Dermatologie und Allergologie
Salzburg, Austria
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Università degli Studi di Modena e Reggio Emilia (UNIMORE)
Modena, Italy
Conditions
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