New drug tested to control rare blood cancers and disorders
NCT ID NCT05552469
Summary
This early-stage study is testing a new oral drug called DFV890 in adults with certain blood and bone marrow disorders, including some forms of myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML). The main goals are to find a safe and tolerable dose and to see if the drug can help reduce the need for blood transfusions and control the disease. About 62 participants will take the drug for at least 24 weeks while doctors closely monitor their health and response.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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H Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612, United States
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Huntsman Cancer Institute
Salt Lake City, Utah, 84112, United States
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Mayo Clinic Rochester
Rochester, Minnesota, 55905, United States
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Memorial Sloan Kettering Cancer Ctr
New York, New York, 10065, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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Novartis Investigative Site
Grenoble, 38043, France
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Novartis Investigative Site
Nantes, 44093, France
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Novartis Investigative Site
Paris, 75475, France
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Novartis Investigative Site
Düsseldorf, North Rhine-Westphalia, 40225, Germany
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Novartis Investigative Site
Dresden, Saxony, 01307, Germany
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Novartis Investigative Site
Leipzig, Saxony, 04103, Germany
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Novartis Investigative Site
Lübeck, 23538, Germany
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Novartis Investigative Site
Hong Kong, 999999, Hong Kong
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Novartis Investigative Site
Brescia, BS, 25123, Italy
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Novartis Investigative Site
Rozzano, MI, 20089, Italy
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Novartis Investigative Site
Singapore, 119074, Singapore
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Novartis Investigative Site
Madrid, 28034, Spain
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Novartis Investigative Site
Cardiff, CF14 4XW, United Kingdom
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Novartis Investigative Site
London, SE5 9RS, United Kingdom
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Novartis Investigative Site
Manchester, M20 2BX, United Kingdom
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Sidney Kimmel CCC At JH
Baltimore, Maryland, 21231, United States
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Stanford Cancer Center
Stanford, California, 94305, United States
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Univ of TX MD Anderson Cancer Cntr
Houston, Texas, 77030, United States
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Vanderbilt University Medical Ctr
Nashville, Tennessee, 37232, United States
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Weill Cornell Medicine NY-Presb
New York, New York, 10021, United States
Conditions
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