New pill targets inflammation to ease arthritic knee pain

NCT ID NCT04886258

Summary

This study tested an experimental oral medicine called DFV890 to see if it could safely reduce pain and inflammation in people with painful knee osteoarthritis. About 115 participants, aged 50-80, took either the medicine or a placebo pill for 12 weeks. Researchers measured changes in knee pain, stiffness, daily function, and signs of inflammation in the knee joint.

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Contacts and locations

Locations

  • ARENSIA Explor Med Res Clinic

    Phoenix, Arizona, 85015, United States

  • Conquest Research

    Winter Park, Florida, 32789, United States

  • Ctr for Adv Research and Education

    Gainesville, Georgia, 30501, United States

  • IRIS Research and Development

    Plantation, Florida, 33324, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Novartis Investigative Site

    CABA, Buenos Aires, C1181ACH, Argentina

  • Novartis Investigative Site

    San Miguel, Tucumán Province, T4000CBC, Argentina

  • Novartis Investigative Site

    San Miguel de Tucumán, 4000, Argentina

  • Novartis Investigative Site

    Brno, Czech Republic, 66250, Czechia

  • Novartis Investigative Site

    Nový Jičín, 741 01, Czechia

  • Novartis Investigative Site

    Prague, 150 06, Czechia

  • Novartis Investigative Site

    Uherské Hradiště, 686 01, Czechia

  • Novartis Investigative Site

    Bad Doberan, 18209, Germany

  • Novartis Investigative Site

    Berlin, 10787, Germany

  • Novartis Investigative Site

    Hamburg, 22143, Germany

  • Novartis Investigative Site

    Hamburg, 22415, Germany

  • Novartis Investigative Site

    Leipzig, 04107, Germany

  • Novartis Investigative Site

    Kecskemét, Bács-Kiskun county, 6044, Hungary

  • Novartis Investigative Site

    Budapest, 1027, Hungary

  • Novartis Investigative Site

    Miskolc, 3526, Hungary

  • Novartis Investigative Site

    Veszprém, 8200, Hungary

  • Novartis Investigative Site

    Cluj-Napoca, Cluj, 400006, Romania

  • Novartis Investigative Site

    Bucharest, 011658, Romania

  • Novartis Investigative Site

    Nové Mesto nad Váhom, 915 01, Slovakia

  • Novartis Investigative Site

    Piešťany, 921 01, Slovakia

  • Novartis Investigative Site

    Sabadell, Barcelona, 08208, Spain

  • Novartis Investigative Site

    Barcelona, Catalonia, 08003, Spain

  • Novartis Investigative Site

    A Coruña, 15006, Spain

  • Novartis Investigative Site

    Seville, 41010, Spain

  • Skylight Health Res Inc Color Spr

    Colorado Springs, Colorado, 80917, United States

  • TriWest Reserach Associates

    El Cajon, California, 92020, United States

Conditions

Explore the condition pages connected to this study.