New drug shows promise for easing knee arthritis pain

NCT ID NCT04886258

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called DFV890 in 115 adults aged 50-80 with painful knee osteoarthritis. Participants received either the drug or a placebo to see if it reduced pain and inflammation. The goal was to find a new way to ease symptoms and improve daily function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ARENSIA Explor Med Res Clinic

    Phoenix, Arizona, 85015, United States

  • Conquest Research

    Winter Park, Florida, 32789, United States

  • Ctr for Adv Research and Education

    Gainesville, Georgia, 30501, United States

  • IRIS Research and Development

    Plantation, Florida, 33324, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Novartis Investigative Site

    CABA, Buenos Aires, C1181ACH, Argentina

  • Novartis Investigative Site

    San Miguel, Tucumán Province, T4000CBC, Argentina

  • Novartis Investigative Site

    San Miguel de Tucumán, 4000, Argentina

  • Novartis Investigative Site

    Brno, Czech Republic, 66250, Czechia

  • Novartis Investigative Site

    Nový Jičín, 741 01, Czechia

  • Novartis Investigative Site

    Prague, 150 06, Czechia

  • Novartis Investigative Site

    Uherské Hradiště, 686 01, Czechia

  • Novartis Investigative Site

    Bad Doberan, 18209, Germany

  • Novartis Investigative Site

    Berlin, 10787, Germany

  • Novartis Investigative Site

    Hamburg, 22143, Germany

  • Novartis Investigative Site

    Hamburg, 22415, Germany

  • Novartis Investigative Site

    Leipzig, 04107, Germany

  • Novartis Investigative Site

    Kecskemét, Bács-Kiskun county, 6044, Hungary

  • Novartis Investigative Site

    Budapest, 1027, Hungary

  • Novartis Investigative Site

    Miskolc, 3526, Hungary

  • Novartis Investigative Site

    Veszprém, 8200, Hungary

  • Novartis Investigative Site

    Cluj-Napoca, Cluj, 400006, Romania

  • Novartis Investigative Site

    Bucharest, 011658, Romania

  • Novartis Investigative Site

    Nové Mesto nad Váhom, 915 01, Slovakia

  • Novartis Investigative Site

    Piešťany, 921 01, Slovakia

  • Novartis Investigative Site

    Sabadell, Barcelona, 08208, Spain

  • Novartis Investigative Site

    Barcelona, Catalonia, 08003, Spain

  • Novartis Investigative Site

    A Coruña, 15006, Spain

  • Novartis Investigative Site

    Seville, 41010, Spain

  • Skylight Health Res Inc Color Spr

    Colorado Springs, Colorado, 80917, United States

  • TriWest Reserach Associates

    El Cajon, California, 92020, United States