New eye drops aim to soothe itchy, damaged eyes from rare allergy condition

NCT ID NCT07395232

First seen Feb 18, 2026 · Last updated May 13, 2026 · Updated 11 times

Summary

This study tests an experimental eye drop, DFL24498, against a placebo in 138 adults with atopic keratoconjunctivitis (AKC), a severe allergic eye disease. The main goal is to see if the drops reduce eye itching and corneal damage over 6 weeks. Participants must have AKC in both eyes and moderate to severe itching.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

Locations

  • AOU Policlinico Umberto I

    RECRUITING

    Roma, 00161, Italy

  • Azienda Ospedaliera Universitaria Integrata Verona

    RECRUITING

    Verona, 37134, Italy

  • Azienda Ospedaliero Universitaria Careggi

    RECRUITING

    Florence, 50134, Italy

  • Baylor University Jamail Specialty Care Center- Alkek Eye Center- Ophthalmology

    RECRUITING

    Houston, Texas, 77030, United States

  • Bowden Eye Associates - Southside Location

    RECRUITING

    Jacksonville, Florida, 32256, United States

  • Clayton Eye Clinical Research

    RECRUITING

    Morrow, Georgia, 30260, United States

  • Duke Eye Center - Ophthalmology

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Fondazione Policlinico Universitario Campus Bio-Medico

    RECRUITING

    Roma, 00128, Italy

  • Fundación de Oftalmología Médica de la Comunitat Valenciana (FOM)

    RECRUITING

    Valencia, 46015, Spain

  • Hospital Universitario Miguel Servet

    RECRUITING

    Zaragoza, 50009, Spain

  • IRCCS AOU di Bologna - Policlinico Sant'Orsola UO Oftalmologia

    RECRUITING

    Bologna, 40138, Italy

  • METAVISION ARRUZAFA S.L. (Hospital Arruzafa)

    RECRUITING

    Córdoba, 14012, Spain

  • Miranza Galicia

    RECRUITING

    Santiago de Compostela, 15706, Spain

  • NYU Langone Health - Eye Center

    RECRUITING

    New York, New York, 10017, United States

  • OBA - Universidad de Valladolid

    RECRUITING

    Valladolid, 47011, Spain

  • Ophthalmology Associates

    RECRUITING

    St Louis, Missouri, 63131, United States

  • Ospedale SS Annunziata, ASL 2 Lanciano Vasto Chieti

    RECRUITING

    Chieti, 66100, Italy

  • Total Eye Care, PA

    RECRUITING

    Memphis, Tennessee, 38119, United States

  • University of Miami, Miller School of Medicine, Bascom Palmer Eye Institute

    RECRUITING

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.