Novartis halts early trial of new cancer drug for business reasons

NCT ID NCT04895748

Summary

This was an early safety study for a new drug called DFF332, designed to block a protein that helps certain cancers grow. It was tested alone and in combinations with other cancer drugs in adults with advanced kidney cancer and other tumors driven by specific genetic changes. The sponsor stopped the trial early for business reasons, not safety, before testing the planned combinations or enrolling most patients.

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Contacts and locations

Locations

  • City of Hope National Medical

    Duarte, California, 91010, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloane Ketterin Cancer Ctr

    New York, New York, 10065, United States

  • Novartis Investigative Site

    Brno, 656 53, Czechia

  • Novartis Investigative Site

    Villejuif, 94800, France

  • Novartis Investigative Site

    Milan, MI, 20133, Italy

  • Novartis Investigative Site

    Koto Ku, Tokyo, 1358550, Japan

  • Novartis Investigative Site

    Singapore, 119228, Singapore

  • Novartis Investigative Site

    Barcelona, 08035, Spain

  • Uni Of TX MD Anderson Cancer Cntr

    Houston, Texas, 77030, United States

  • WA Uni School Of Med

    St Louis, Missouri, 63110, United States

Conditions

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