First test of new cancer fighter DF6002 shows early promise

NCT ID NCT04423029

Summary

This first-in-human study tested a new drug called DF6002 in 170 patients with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find safe dose levels and see if the drug, given alone or with an existing immunotherapy (nivolumab), could shrink tumors. As an early Phase 1 trial, it focused on establishing safety and gathering initial signs of effectiveness.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Atlantic Health System

    Morristown, New Jersey, 07960, United States

  • Augusta University Georgia Cancer Center

    Augusta, Georgia, 30912-0003, United States

  • Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Centre Hospitalier Lyon-Sud

    Pierre-Bénite, 69495, France

  • Clinica Universidad de Navarra - Madrid

    Madrid, 28027, Spain

  • Clinica Universidad de Navarra - Pamplona

    Pamplona, 31008, Spain

  • Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Gustave Roussy

    Villejuif, 94805, France

  • HealthPartners Cancer Center at Regions Hospital

    Saint Paul, Minnesota, 55101, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Hospital Universitari Vall d'Hebrón

    Barcelona, 08035, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, 28034, Spain

  • Huntsman Cancer Institute and Hospital

    Salt Lake City, Utah, 84112, United States

  • Hôpital Saint-Louis

    Paris, 75010, France

  • Institut Bergonié

    Bordeaux, 33000, France

  • Local Institution

    Boston, Massachusetts, 02215, United States

  • Local Institution - 0022

    Heidelberg, 3084, Australia

  • Local Institution - 0023

    Box Hill, 3128, Australia

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, 14263, United States

  • SCRI - HealthOne Denver

    Denver, Colorado, 80218, United States

  • SCRI - Tennessee Oncology - Saint Thomas West Clinic

    Nashville, Tennessee, 37205, United States

  • START Madrid - Hospital Universitario Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States

  • USOR - Virginia Cancer Specialists - Fairfax Office

    Fairfax, Virginia, 22031, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California Irvine

    Orange, California, 92868, United States

  • University of Iowa Hospitals and Clinics

    Iowa City, Iowa, 52242, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Yale School of Medicine

    New Haven, Connecticut, 06520, United States

Conditions

Explore the condition pages connected to this study.