Cheap drugs may prevent dangerous spikes when removing breathing tubes
NCT ID NCT07651657
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests two common drugs, dexmedetomidine and lignocaine, to see which better prevents sudden increases in heart rate and blood pressure when a breathing tube is removed after surgery. Sixty healthy adults undergoing elective surgery will receive one of the drugs 10 minutes before tube removal. The goal is to find a safe, affordable option for hospitals with limited resources.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine and lignocaine
What this could lead to
If it works, this could point toward a safer, low-cost method to prevent dangerous heart rate and blood pressure spikes during breathing tube removal after surgery.
What could go wrong
This is a small, early-stage trial with only 60 healthy adults, so results may not apply to sicker or older patients. The drugs may not work as expected or could cause side effects like low blood pressure or slow heart rate.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo hospital Lahore
Lahore, Punjab Province, 54000, Pakistan
Contact Phone: •••-•••-•••• Email: •••••@•••••