Could a simple additive ease Post-Surgery pain?
NCT ID NCT07176065
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether adding dexmedetomidine to a standard numbing medication (ropivacaine) can improve pain control and recovery in 60 adults undergoing total knee replacement. Participants will receive either the standard injection or the combination, and researchers will measure pain scores, opioid use, and side effects for 24 hours after surgery. The goal is to find a safer, more effective way to manage post-operative pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dexmedetomidine added to ropivacaine
- What this could lead to
- If it works, this could offer a simple way to reduce pain and opioid use after knee replacement, helping patients recover more comfortably.
- What could go wrong
- This is a small pilot study (60 people) testing a single dose. Results may not apply to all patients, and the benefit over standard care may be small or absent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Universiti Malaya Medical Centre
Kuala Lumpur, Kuala Lumpur, 59100, Malaysia
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