Could a simple additive ease Post-Surgery pain?
NCT ID NCT07176065
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether adding dexmedetomidine to a standard numbing medication (ropivacaine) can improve pain control and recovery in 60 adults undergoing total knee replacement. Participants will receive either the standard injection or the combination, and researchers will measure pain scores, opioid use, and side effects for 24 hours after surgery. The goal is to find a safer, more effective way to manage post-operative pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine added to ropivacaine
What this could lead to
If it works, this could offer a simple way to reduce pain and opioid use after knee replacement, helping patients recover more comfortably.
What could go wrong
This is a small pilot study (60 people) testing a single dose. Results may not apply to all patients, and the benefit over standard care may be small or absent.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Universiti Malaya Medical Centre
Kuala Lumpur, Kuala Lumpur, 59100, Malaysia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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