Could a Two-Day steroid course replace five days for severe asthma in kids?

NCT ID NCT07731217

Completed Disease control Sponsor: Istanbul Medeniyet University Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial tests whether a two-day course of intravenous dexamethasone works as well as a standard five-day course of methylprednisolone for children having a severe asthma attack. Children aged 2 to 18 with a severe exacerbation are randomly assigned to one of the two treatments. Researchers measure breathing improvement using a standard asthma severity score at the 4-hour mark and two days after discharge.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: intravenous dexamethasone compared with intravenous methylprednisolone
What this could lead to: If dexamethasone works as well as the standard longer treatment, children with severe asthma attacks could receive a shorter, simpler steroid course.
What could go wrong: This is a single-center trial with 129 children, so results may not apply to all patients. Dexamethasone might prove less effective or have different side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ASTHMA (DIAGNOSIS) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

asthma disease status asthmaticus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA (DIAGNOSIS) ASTHMA EXACERBATIONS STATUS ASTHMATICUS

Contacts and locations

Locations

Istanbul Goztepe Prof. Dr. Suleyman Yalcin City Hospital

Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.