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Simple spray cuts pain after hernia surgery, study finds

NCT ID NCT07208253

Symptom relief Sponsor: Gürkan Değirmencioğlu Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether spraying a mix of two common medicines, dexamethasone and bupivacaine, onto the surgical mesh during laparoscopic hernia repair could reduce pain afterward. 175 adults having elective hernia surgery were randomly assigned to receive the spray or no local treatment. Those who got the spray reported less pain, needed fewer extra painkillers, and were more satisfied with their recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone and bupivacaine
What this could lead to
If confirmed, this simple spray could become a standard way to ease pain and improve comfort after laparoscopic hernia surgery.
What could go wrong
This is a single completed study with 175 patients. The results may not apply to all hernia surgeries or patients, and the long-term effects are not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

175 people

The number who actually took part.

Started

Apr 2021

Finished

Jan 2023

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (≥18 years old) scheduled for elective unilateral inguinal hernia repair with the laparoscopic total extraperitoneal (TEP) technique * American Society of Anesthesiologists (ASA) physical status I-II * Ability to provide informed consent Exclusion Criteria: * Age \<18 years * ASA physical status ≥III * Recurrent or bilateral inguinal hernia * History of allergy to local anesthetics or corticosteroids * Chronic opioid use or dependence * Severe hepatic, renal, or cardiac disease * Pregnancy or breastfeeding * Patients who declined to participate or could not provide consent

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Conditions

The condition(s) this trial relates to.

Hernia, Inguinal Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inguinal hernia repair (not urgent)

Contacts and locations

Locations

  • Etlik City Hospital (Etlik Şehir Hastanesi)

    Ankara, Ankara, 06010, Turkey (Türkiye)

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