New pill could clear psoriasis in teens

NCT ID NCT06979453

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a daily pill called deucravacitinib in teenagers aged 12 to 18 with moderate to severe plaque psoriasis. About 366 participants will receive either the drug or a placebo. The main goals are to see if the drug improves skin clearance by at least 75% and reduces overall severity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Deucravacitinib

What this could lead to

If successful, this could provide a new oral treatment option for teenagers with moderate to severe plaque psoriasis, helping clear skin and reduce itching.

What could go wrong

This is a phase 3 trial, but results may not apply to all teens. Side effects are possible, and the drug may not work better than placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

exanthem Pruritus psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • "DERMED" Centrum Medyczne Sp. z o.o.

    RECRUITING

    Lodz, 90-265, Poland

    Contact Phone: •••-•••-••••

  • Advanced Medical Research, PC.

    RECRUITING

    Sandy Springs, Georgia, 30328, United States

    Contact Phone: •••-•••-••••

  • Alberta Dermasurgery Centre

    RECRUITING

    Edmonton, Alberta, T6G 1C3, Canada

    Contact Phone: •••-•••-••••

  • Apex Clinical Research Center

    RECRUITING

    Mayfield Heights, Ohio, 44124, United States

    Contact Phone: •••-•••-••••

  • Apex Clinical Research Center - Canton

    RECRUITING

    Canton, Ohio, 44716, United States

    Contact Phone: •••-•••-••••

  • AvantDerm

    RECRUITING

    Toronto, Ontario, M5A 3R6, Canada

    Contact Phone: •••-•••-••••

  • BAG Drs. Med. Quist PartG

    RECRUITING

    Mainz, Rhineland-Palatinate, 55128, Germany

    Contact Phone: •••-•••-••••

  • Beijing Children's hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100045, China

    Contact Phone: •••-•••-••••

  • CHUS - Hospital Clinico Universitario

    RECRUITING

    Santiago de Compostela, 15706, Spain

    Contact Phone: •••-•••-••••

  • CONEXA Investigacion Clinica S.A.

    RECRUITING

    Buenos Aires, 1012, Argentina

    Contact Phone: •••-•••-••••

  • Center For Dermatology Clinical Research, Inc.

    RECRUITING

    Fremont, California, 94538, United States

    Contact Phone: •••-•••-••••

  • Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman

    RECRUITING

    Liège, 4000, Belgium

    Contact Phone: •••-•••-••••

  • Centro de Investigaciones Médicas Tucuman

    RECRUITING

    SAN M. de Tucuman, Tucumán Province, T4000AXL, Argentina

    Contact Phone: •••-•••-••••

  • Centrul de Medicina de Familie

    RECRUITING

    Iași, 700556, Romania

    Contact Phone: •••-•••-••••

  • Chang Gung Medical Foundation-Linkou Branch

    RECRUITING

    Taoyuan, 333, Taiwan

    Contact Phone: •••-•••-••••

  • Chang Gung Memorial Hospital at Kaohsiung

    RECRUITING

    Kaohsiung Niao Sung Dist, Kaohsiung, 83301, Taiwan

    Contact Phone: •••-•••-••••

  • Charité Universitaetsmedizin Berlin - Campus Mitte

    RECRUITING

    Berlin, 10117, Germany

    Contact Phone: •••-•••-••••

  • Clinexpert Kft.

    RECRUITING

    Budapest, Pest County, 1033, Hungary

    Contact Phone: •••-•••-••••

  • Cliniques universitaires Saint-Luc

    RECRUITING

    Brussels, Bruxelles-Capitale, Région de, 1200, Belgium

    Contact Phone: •••-•••-••••

  • Dawes Fretzin Clinical Research Group, LLC

    RECRUITING

    Indianapolis, Indiana, 46250, United States

    Contact Phone: •••-•••-••••

  • Debreceni Egyetem Klinikai Kozpont

    RECRUITING

    Debrecen, 4032, Hungary

    Contact Phone: •••-•••-••••

  • DermEffects

    RECRUITING

    London, Ontario, N6H 5L5, Canada

    Contact Phone: •••-•••-••••

  • Derma Internacional

    RECRUITING

    Buenos Aires, 1426, Argentina

    Contact Phone: •••-•••-••••

  • Dermatology Affiliates Research Institute

    RECRUITING

    Atlanta, Georgia, 30305, United States

    Contact Phone: •••-•••-••••

  • Dermatology Research Associates

    RECRUITING

    Los Angeles, California, 90045, United States

    Contact Phone: •••-•••-••••

  • Dermatology and Skin Cancer Specialists, LLC

    RECRUITING

    Rockville, Maryland, 20850, United States

    Contact Phone: •••-•••-••••

  • ETYKA Osrodek Badan Klinicznych

    RECRUITING

    Olsztyn, 10-117, Poland

    Contact Phone: •••-•••-••••

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore

    RECRUITING

    Roma, 00168, Italy

    Contact Phone: •••-•••-••••

  • Frontier Derm Partners

    RECRUITING

    Mill Creek, Washington, 98012, United States

    Contact Phone: •••-•••-••••

  • FutureMeds - Targowek

    RECRUITING

    Warsaw, Masovian Voivodeship, 03-291, Poland

    Contact Phone: •••-•••-••••

  • GCM Medical Group, PSC - Hato Rey Site

    RECRUITING

    San Juan, 00917, Puerto Rico

    Contact Phone: •••-•••-••••

  • Golden State Dermatology - Walnut Creek - Ygnacio Valley Road

    RECRUITING

    Walnut Creek, California, 94598, United States

    Contact Phone: •••-•••-••••

  • Grupo Dermatológico y Estético Pedro Jaén S.A

    RECRUITING

    Madrid, 28002, Spain

    Contact Phone: •••-•••-••••

  • Guangdong Province Dermatology Hospital

    RECRUITING

    Guangzhou, Guangdong, 510018, China

    Contact Phone: •••-•••-••••

  • Hospital Italiano de Buenos Aires

    RECRUITING

    Buenos Aires, 1181, Argentina

    Contact Phone: •••-•••-••••

  • Hospital Moinhos de Vento

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90560-032, Brazil

    Contact Phone: •••-•••-••••

  • Hospital Sant Joan de Déu

    RECRUITING

    Esplugues de Llobregat, Barcelona [Barcelona], 08950, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

    Contact Phone: •••-•••-••••

  • Hospital de Niños Dr. Ricardo Gutiérrez

    RECRUITING

    Buenos Aires, 1425, Argentina

    Contact Phone: •••-•••-••••

  • Hunan Children's Hospital

    RECRUITING

    Changsha, Hunan, 410007, China

    Contact Phone: •••-•••-••••

  • Instituto de Neumonologia Y Dermatologia

    RECRUITING

    Ciudad Autonoma de Buenos Aires, Buenos Aires, 1425, Argentina

    Contact Phone: •••-•••-••••

  • JDR Dermatology Research

    RECRUITING

    Las Vegas, Nevada, 89148, United States

    Contact Phone: •••-•••-••••

  • Kaohsiung Veterans General Hospital

    RECRUITING

    Kaohsiung City, 81362, Taiwan

    Contact Phone: •••-•••-••••

  • Kentucky Advanced Medical Research LLC

    RECRUITING

    Murray, Kentucky, 42071, United States

    Contact

  • Klinika Ambroziak Dermatologia

    RECRUITING

    Warsaw, 02-953, Poland

    Contact Phone: •••-•••-••••

  • Kuchnir Dermatology & Dermatologic Surgery

    RECRUITING

    Milford, Massachusetts, 01757, United States

    Contact Phone: •••-•••-••••

  • Life Clinical Trials

    RECRUITING

    Margate, Florida, 33063, United States

    Contact Phone: •••-•••-••••

  • Local Institution - 0008

    NOT_YET_RECRUITING

    Caguas, 00725, Puerto Rico

    Contact

  • Local Institution - 0021

    NOT_YET_RECRUITING

    Clearwater, Florida, 33756, United States

    Contact

  • Local Institution - 0025

    NOT_YET_RECRUITING

    Fountain Valley, California, 92708, United States

    Contact

  • Local Institution - 0041

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35243, United States

    Contact

  • Local Institution - 0045

    NOT_YET_RECRUITING

    Norfolk, Virginia, 23502, United States

    Contact

  • Local Institution - 0053

    ACTIVE_NOT_RECRUITING

    Phoenix, Arizona, 85006, United States

  • Local Institution - 0077

    NOT_YET_RECRUITING

    Sacramento, California, 95814, United States

    Contact

  • Local Institution - 0095

    NOT_YET_RECRUITING

    Detroit, Michigan, 48201, United States

    Contact

  • Local Institution - 0096

    NOT_YET_RECRUITING

    Veracruz, 91910, Mexico

    Contact

  • Local Institution - 0124

    NOT_YET_RECRUITING

    Medellín, Antioquia, 50021, Colombia

    Contact

  • Local Institution - 0125

    NOT_YET_RECRUITING

    Bogota, Cundinamarca, 111 411, Colombia

    Contact

  • Local Institution - 0137

    NOT_YET_RECRUITING

    Salvador, Estado de Bahia, 41820-020, Brazil

    Contact

  • Local Institution - 0140

    NOT_YET_RECRUITING

    Barretos, São Paulo, 14784400, Brazil

    Contact

  • Local Institution - 0142

    NOT_YET_RECRUITING

    Montreal, Quebec, H3T 1C5, Canada

    Contact

  • Local Institution - 0155

    NOT_YET_RECRUITING

    Monterrey, Nuevo León, 64718, Mexico

    Contact

  • Local Institution - 0163

    NOT_YET_RECRUITING

    Ribeirão Preto, São Paulo, 14051-140, Brazil

    Contact

  • Local Institution - 0164

    NOT_YET_RECRUITING

    Winnipeg, Manitoba, R3C 0N2, Canada

    Contact

  • Local Institution - 0166

    NOT_YET_RECRUITING

    The Bronx, New York, 10467, United States

    Contact

  • Local Institution - 0167

    NOT_YET_RECRUITING

    Barranquilla, Atlántico, 080002, Colombia

    Contact

  • Local Institution - 0170

    NOT_YET_RECRUITING

    São Paulo, 05403-000, Brazil

    Contact

  • Local Institution - 0174

    WITHDRAWN

    Bucharest, Bucharest, 020125, Romania

  • Local Institution - 0177

    WITHDRAWN

    Lublin, Lublin Voivodeship, 20-573, Poland

  • Local Institution - 0182

    NOT_YET_RECRUITING

    Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

    Contact

  • Local Institution - 0198

    NOT_YET_RECRUITING

    Barcelona, Catalunya [Cataluña], 08041, Spain

    Contact

  • Local Institution - 0202

    NOT_YET_RECRUITING

    Metairie, Louisiana, 70001, United States

    Contact

  • Local Institution - 0205

    NOT_YET_RECRUITING

    New York, New York, 10075, United States

    Contact

  • Local Institution - 0210

    WITHDRAWN

    Brussels, Bruxelles-Capitale, Région de, 1200, Belgium

  • Local Institution - 0213

    WITHDRAWN

    Bucharest, Bucharest, 30463, Romania

  • Local Institution - 0225

    NOT_YET_RECRUITING

    Medellín, Antioquia, 050012, Colombia

    Contact

  • Local Institution - 0227

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450003, China

    Contact

  • Local Institution - 0228

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 610091, China

    Contact

  • Local Institution - 0233

    NOT_YET_RECRUITING

    Columbia, Missouri, 65201, United States

    Contact

  • Local Institution - 0234

    COMPLETED

    Hickory, North Carolina, 28602, United States

  • Local Institution - 0238

    NOT_YET_RECRUITING

    Zapopan, Jalisco, 45190, Mexico

    Contact

  • Local Institution - 0240

    NOT_YET_RECRUITING

    Toronto, Ontario, M5G 1X8, Canada

    Contact

  • Local Institution - 0248

    COMPLETED

    Nashville, Tennessee, 37205, United States

  • Local Institution - 0253

    NOT_YET_RECRUITING

    Mexico City, Mexico City, 06720, Mexico

    Contact

  • Local Institution - 0254

    NOT_YET_RECRUITING

    Bayamón, 00960, Puerto Rico

    Contact

  • Local Institution - 0257

    NOT_YET_RECRUITING

    Mérida, 97070, Mexico

    Contact

  • Local Institution - 0258

    NOT_YET_RECRUITING

    Toluca, 50010, Mexico

    Contact

  • Local Institution - 0259

    NOT_YET_RECRUITING

    Chihuahua City, 31217, Mexico

    Contact

  • Local Institution - 0261

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35203, United States

    Contact

  • Local Institution - 0264

    NOT_YET_RECRUITING

    Spokane, Washington, 99204, United States

    Contact

  • Local Institution - 0265

    NOT_YET_RECRUITING

    Jinan, Shandong, 250022, China

    Contact

  • Local Institution - 0266

    NOT_YET_RECRUITING

    Lee's Summit, Missouri, 64064, United States

    Contact

  • Local Institution - 0271

    NOT_YET_RECRUITING

    Columbus, Ohio, 43228, United States

    Contact

  • Local Institution - 0275

    NOT_YET_RECRUITING

    Lorain, Ohio, 44053, United States

    Contact

  • Local Institution - 0278

    NOT_YET_RECRUITING

    Columbia, Missouri, 65212, United States

    Contact

  • Local Institution - 0280

    NOT_YET_RECRUITING

    Southlake, Texas, 76092, United States

    Contact

  • Local Institution - 0281

    NOT_YET_RECRUITING

    Robbinsville, New Jersey, 08691, United States

    Contact

  • Local Institution - 0282

    NOT_YET_RECRUITING

    Gdansk, Pomeranian Voivodeship, 80-546, Poland

    Contact

  • Local Institution - 0283

    NOT_YET_RECRUITING

    Clifton, New Jersey, 07013, United States

    Contact

  • Lotus-Med Tunari

    RECRUITING

    Bucharest, Bucharest, 020528, Romania

    Contact Phone: •••-•••-••••

  • MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research

    RECRUITING

    Tampa, Florida, 33607, United States

    Contact Phone: •••-•••-••••

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 10002, Taiwan

    Contact Phone: •••-•••-••••

  • New Derm Clinical SRL

    RECRUITING

    Timișoara, 300757, Romania

    Contact Phone: •••-•••-••••

  • Northridge Clinical Trials

    RECRUITING

    Northridge, California, 91325, United States

    Contact Phone: •••-•••-••••

  • ObjectiveHealth - Goodlettsville Dermatology Research

    RECRUITING

    Goodlettsville, Tennessee, 37072, United States

    Contact Phone: •••-•••-••••

  • Paddington Testing Company

    RECRUITING

    Philadelphia, Pennsylvania, 19103, United States

    Contact Phone: •••-•••-••••

  • Paradigm Clinical Research, LLC

    RECRUITING

    Wheat Ridge, Colorado, 80033, United States

    Contact Phone: •••-•••-••••

  • Peking University Third Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100091, China

    Contact Phone: •••-•••-••••

  • Policlinica Providența

    RECRUITING

    Iași, 700259, Romania

    Contact Phone: •••-•••-••••

  • Psoriahue

    RECRUITING

    Ciudad Autonoma de Buenos Aires, Buenos Aires, C1425DKG, Argentina

    Contact Phone: •••-•••-••••

  • Royalderm Agnieszka Nawrocka

    RECRUITING

    Warsaw, 02-962, Poland

    Contact Phone: •••-•••-••••

  • SPECDERM Poznanska sp.j.

    RECRUITING

    Bialystok, Podlaskie Voivodeship, 15-375, Poland

    Contact Phone: •••-•••-••••

  • Shanghai Skin Disease Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200443, China

    Contact Phone: •••-•••-••••

  • Skin Research of South Florida

    RECRUITING

    Miami, Florida, 33173, United States

    Contact Phone: •••-•••-••••

  • Skincare Studio

    RECRUITING

    St. John's, Newfoundland and Labrador, A1E 1V4, Canada

    Contact Phone: •••-•••-••••

  • Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ

    RECRUITING

    Szeged, Csongrád megye, 6720, Hungary

    Contact Phone: •••-•••-••••

  • Texas Dermatology and Laser Specialists

    RECRUITING

    San Antonio, Texas, 78218, United States

    Contact Phone: •••-•••-••••

  • The Affiliated Hospital of Hebei University of Engineering

    RECRUITING

    Handan, Hebei, 56029, China

    Contact Phone: •••-•••-••••

  • The Centre for Dermatology

    RECRUITING

    Richmond Hill, Ontario, L4B 1A5, Canada

    Contact Phone: •••-•••-••••

  • The First People's Hospital of Hangzhou

    RECRUITING

    Hangzhou, Zhejiang, 310006, China

    Contact Phone: •••-•••-••••

  • The University of Hong Kong-Shenzhen Hospital

    RECRUITING

    Shenzhen, Guangdong, 518053, China

    Contact Phone: •••-•••-••••

  • USF Health

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact Phone: •••-•••-••••

  • UZ Gent

    RECRUITING

    Ghent, Oost-Vlaanderen, 9000, Belgium

    Contact Phone: •••-•••-••••

  • Universitaetsklinikum Carl Gustav Carus Dresden

    RECRUITING

    Dresden, 01307, Germany

    Contact Phone: •••-•••-••••

  • Universitaetsklinikum Erlangen

    RECRUITING

    Erlangen, 91054, Germany

    Contact Phone: •••-•••-••••

  • Universitätsklinikum Münster

    RECRUITING

    Münster, North Rhine-Westphalia, 48149, Germany

    Contact Phone: •••-•••-••••

  • Wellness Clinical Research

    RECRUITING

    Miami Lakes, Florida, 33016, United States

    Contact Phone: •••-•••-••••