New pill could clear psoriasis in teens

NCT ID NCT06979453

First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 5 times

Summary

This study tests a daily pill called deucravacitinib in teenagers aged 12 to 18 with moderate to severe plaque psoriasis. About 366 participants will receive either the drug or a placebo. The main goals are to see if the drug improves skin clearance by at least 75% and reduces overall severity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Deucravacitinib
What this could lead to
If successful, this could provide a new oral treatment option for teenagers with moderate to severe plaque psoriasis, helping clear skin and reduce itching.
What could go wrong
This is a phase 3 trial, but results may not apply to all teens. Side effects are possible, and the drug may not work better than placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • "DERMED" Centrum Medyczne Sp. z o.o.

    RECRUITING

    Lodz, 90-265, Poland

  • Advanced Medical Research, PC.

    RECRUITING

    Sandy Springs, Georgia, 30328, United States

  • Alberta Dermasurgery Centre

    RECRUITING

    Edmonton, Alberta, T6G 1C3, Canada

  • Apex Clinical Research Center

    RECRUITING

    Lorain, Ohio, 44053, United States

  • Apex Clinical Research Center

    RECRUITING

    Mayfield Heights, Ohio, 44124, United States

  • Apex Clinical Research Center - Canton

    RECRUITING

    Canton, Ohio, 44716, United States

  • Arké SMO S.A de C.V

    RECRUITING

    Veracruz, 91910, Mexico

  • AvantDerm

    RECRUITING

    Toronto, Ontario, M5A 3R6, Canada

  • BAG Drs. Med. Quist PartG

    RECRUITING

    Mainz, Rhineland-Palatinate, 55128, Germany

  • Beijing Children's hospital, Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100045, China

  • CHUS - Hospital Clinico Universitario

    RECRUITING

    Santiago de Compostela, 15706, Spain

  • CONEXA Investigacion Clinica S.A.

    RECRUITING

    Buenos Aires, 1012, Argentina

  • Center For Dermatology Clinical Research, Inc.

    RECRUITING

    Fremont, California, 94538, United States

  • Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman

    RECRUITING

    Liège, 4000, Belgium

  • Centro de Investigaciones Médicas Tucuman

    RECRUITING

    SAN M. de Tucuman, Tucumán Province, T4000AXL, Argentina

  • Centrul de Medicina de Familie

    RECRUITING

    Iași, 700556, Romania

  • Chang Gung Medical Foundation-Linkou Branch

    RECRUITING

    Taoyuan, 333, Taiwan

  • Chang Gung Memorial Hospital at Kaohsiung

    RECRUITING

    Kaohsiung Niao Sung Dist, Kaohsiung, 83301, Taiwan

  • Charité Universitaetsmedizin Berlin - Campus Mitte

    RECRUITING

    Berlin, 10117, Germany

  • Clinexpert Kft.

    RECRUITING

    Budapest, Pest County, 1033, Hungary

  • Cliniques universitaires Saint-Luc

    RECRUITING

    Brussels, Bruxelles-Capitale, Région de, 1200, Belgium

  • Dawes Fretzin Clinical Research Group, LLC

    RECRUITING

    Indianapolis, Indiana, 46250, United States

  • Debreceni Egyetem Klinikai Kozpont

    RECRUITING

    Debrecen, 4032, Hungary

  • DermEffects

    RECRUITING

    London, Ontario, N6H 5L5, Canada

  • Derma Internacional

    RECRUITING

    Buenos Aires, 1426, Argentina

  • Dermatology Affiliates Research Institute

    RECRUITING

    Atlanta, Georgia, 30305, United States

  • Dermatology Research Associates

    RECRUITING

    Los Angeles, California, 90045, United States

  • Dermatology and Skin Cancer Center

    RECRUITING

    Lee's Summit, Missouri, 64064, United States

  • Dermatology and Skin Cancer Specialists, LLC

    RECRUITING

    Rockville, Maryland, 20850, United States

  • ETYKA Osrodek Badan Klinicznych

    RECRUITING

    Olsztyn, 10-117, Poland

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore

    RECRUITING

    Roma, 00168, Italy

  • Frontier Derm Partners

    RECRUITING

    Mill Creek, Washington, 98012, United States

  • FutureMeds - Targowek

    RECRUITING

    Warsaw, Masovian Voivodeship, 03-291, Poland

  • GCM Medical Group, PSC - Hato Rey Site

    RECRUITING

    San Juan, 00917, Puerto Rico

  • Golden State Dermatology - Walnut Creek - Ygnacio Valley Road

    RECRUITING

    Walnut Creek, California, 94598, United States

  • Grupo Dermatológico y Estético Pedro Jaén S.A

    RECRUITING

    Madrid, 28002, Spain

  • Guangdong Province Dermatology Hospital

    RECRUITING

    Guangzhou, Guangdong, 510018, China

  • Henry Ford Medical Center

    RECRUITING

    Detroit, Michigan, 48202-3141, United States

  • Hospital Italiano de Buenos Aires

    RECRUITING

    Buenos Aires, 1181, Argentina

  • Hospital Moinhos de Vento

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90560-032, Brazil

  • Hospital Sant Joan de Déu

    RECRUITING

    Esplugues de Llobregat, Barcelona [Barcelona], 08950, Spain

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) - HCFMRP

    RECRUITING

    Ribeirão Preto, São Paulo, 14051-140, Brazil

  • Hospital de Niños Dr. Ricardo Gutiérrez

    RECRUITING

    Buenos Aires, 1425, Argentina

  • Hospital de la Santa Creu i Sant Pau

    RECRUITING

    Barcelona, Catalunya [Cataluña], 08041, Spain

  • Hunan Children's Hospital

    RECRUITING

    Changsha, Hunan, 410007, China

  • Instituto Dermatologico de Jalisco

    RECRUITING

    Zapopan, Jalisco, 45190, Mexico

  • Instituto de Neumonologia Y Dermatologia

    RECRUITING

    Ciudad Autonoma de Buenos Aires, Buenos Aires, 1425, Argentina

  • JDR Dermatology Research

    RECRUITING

    Las Vegas, Nevada, 89148, United States

  • Kaohsiung Veterans General Hospital

    RECRUITING

    Kaohsiung City, 81362, Taiwan

  • Kentucky Advanced Medical Research LLC

    RECRUITING

    Murray, Kentucky, 42071, United States

  • Klinika Ambroziak Dermatologia

    RECRUITING

    Warsaw, 02-953, Poland

  • Kuchnir Dermatology & Dermatologic Surgery

    RECRUITING

    Milford, Massachusetts, 01757, United States

  • Life Clinical Trials

    RECRUITING

    Margate, Florida, 33063, United States

  • Local Institution - 0008

    NOT_YET_RECRUITING

    Caguas, 00725, Puerto Rico

  • Local Institution - 0021

    NOT_YET_RECRUITING

    Clearwater, Florida, 33756, United States

  • Local Institution - 0025

    NOT_YET_RECRUITING

    Fountain Valley, California, 92708, United States

  • Local Institution - 0041

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35243, United States

  • Local Institution - 0045

    NOT_YET_RECRUITING

    Norfolk, Virginia, 23502, United States

  • Local Institution - 0053

    ACTIVE_NOT_RECRUITING

    Phoenix, Arizona, 85006, United States

  • Local Institution - 0077

    NOT_YET_RECRUITING

    Sacramento, California, 95814, United States

  • Local Institution - 0095

    NOT_YET_RECRUITING

    Detroit, Michigan, 48201, United States

  • Local Institution - 0124

    NOT_YET_RECRUITING

    Medellín, Antioquia, 50021, Colombia

  • Local Institution - 0125

    NOT_YET_RECRUITING

    Bogota, Cundinamarca, 111 411, Colombia

  • Local Institution - 0137

    NOT_YET_RECRUITING

    Salvador, Estado de Bahia, 41820-020, Brazil

  • Local Institution - 0142

    NOT_YET_RECRUITING

    Montreal, Quebec, H3T 1C5, Canada

  • Local Institution - 0155

    NOT_YET_RECRUITING

    Monterrey, Nuevo León, 64718, Mexico

  • Local Institution - 0164

    NOT_YET_RECRUITING

    Winnipeg, Manitoba, R3C 0N2, Canada

  • Local Institution - 0166

    NOT_YET_RECRUITING

    The Bronx, New York, 10467, United States

  • Local Institution - 0167

    NOT_YET_RECRUITING

    Barranquilla, Atlántico, 080002, Colombia

  • Local Institution - 0170

    NOT_YET_RECRUITING

    São Paulo, 05403-000, Brazil

  • Local Institution - 0174

    WITHDRAWN

    Bucharest, Bucharest, 020125, Romania

  • Local Institution - 0177

    WITHDRAWN

    Lublin, Lublin Voivodeship, 20-573, Poland

  • Local Institution - 0182

    NOT_YET_RECRUITING

    Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

  • Local Institution - 0187

    NOT_YET_RECRUITING

    Rome, Lazio, 00133, Italy

  • Local Institution - 0202

    NOT_YET_RECRUITING

    Metairie, Louisiana, 70001, United States

  • Local Institution - 0205

    NOT_YET_RECRUITING

    New York, New York, 10075, United States

  • Local Institution - 0210

    WITHDRAWN

    Brussels, Bruxelles-Capitale, Région de, 1200, Belgium

  • Local Institution - 0213

    WITHDRAWN

    Bucharest, Bucharest, 30463, Romania

  • Local Institution - 0225

    NOT_YET_RECRUITING

    Medellín, Antioquia, 050012, Colombia

  • Local Institution - 0228

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 610091, China

  • Local Institution - 0233

    NOT_YET_RECRUITING

    Columbia, Missouri, 65201, United States

  • Local Institution - 0234

    COMPLETED

    Hickory, North Carolina, 28602, United States

  • Local Institution - 0240

    NOT_YET_RECRUITING

    Toronto, Ontario, M5G 1X8, Canada

  • Local Institution - 0248

    COMPLETED

    Nashville, Tennessee, 37205, United States

  • Local Institution - 0253

    NOT_YET_RECRUITING

    Mexico City, Mexico City, 06720, Mexico

  • Local Institution - 0254

    NOT_YET_RECRUITING

    Bayamón, 00960, Puerto Rico

  • Local Institution - 0257

    NOT_YET_RECRUITING

    Mérida, 97070, Mexico

  • Local Institution - 0258

    NOT_YET_RECRUITING

    Toluca, 50010, Mexico

  • Local Institution - 0259

    NOT_YET_RECRUITING

    Chihuahua City, 31217, Mexico

  • Local Institution - 0261

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35203, United States

  • Local Institution - 0264

    NOT_YET_RECRUITING

    Spokane, Washington, 99204, United States

  • Local Institution - 0265

    NOT_YET_RECRUITING

    Jinan, Shandong, 250022, China

  • Local Institution - 0271

    NOT_YET_RECRUITING

    Ammon, Idaho, 83406, United States

  • Local Institution - 0273

    NOT_YET_RECRUITING

    Brooklyn, New York, 11203, United States

  • Local Institution - 0278

    NOT_YET_RECRUITING

    Columbia, Missouri, 65212, United States

  • Local Institution - 0280

    NOT_YET_RECRUITING

    Southlake, Texas, 76092, United States

  • Local Institution - 0281

    NOT_YET_RECRUITING

    Robbinsville, New Jersey, 08691, United States

  • Local Institution - 0282

    NOT_YET_RECRUITING

    Gdansk, Pomeranian Voivodeship, 80-546, Poland

  • Local Institution - 0283

    NOT_YET_RECRUITING

    Clifton, New Jersey, 07013, United States

  • Local Institution - 0284

    NOT_YET_RECRUITING

    Campinas, São Paulo, 13086-888, Brazil

  • Local Institution - 0285

    NOT_YET_RECRUITING

    Bucharest, Bucharest, 030463, Romania

  • Local Institution - 0286

    NOT_YET_RECRUITING

    Cluj-Napoca, 400006, Romania

  • Lotus-Med Tunari

    RECRUITING

    Bucharest, Bucharest, 020528, Romania

  • MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research

    RECRUITING

    Tampa, Florida, 33607, United States

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 10002, Taiwan

  • New Derm Clinical SRL

    RECRUITING

    Timișoara, 300757, Romania

  • Northridge Clinical Trials

    RECRUITING

    Northridge, California, 91325, United States

  • ObjectiveHealth - Goodlettsville Dermatology Research

    RECRUITING

    Goodlettsville, Tennessee, 37072, United States

  • Paddington Testing Company

    RECRUITING

    Philadelphia, Pennsylvania, 19103, United States

  • Paradigm Clinical Research, LLC

    RECRUITING

    Wheat Ridge, Colorado, 80033, United States

  • Peking University Third Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100091, China

  • People's Hospital of Henan Province

    RECRUITING

    Zhengzhou, Henan, 450003, China

  • Policlinica Providența

    RECRUITING

    Iași, 700259, Romania

  • Psoriahue

    RECRUITING

    Ciudad Autonoma de Buenos Aires, Buenos Aires, C1425DKG, Argentina

  • Royalderm Agnieszka Nawrocka

    RECRUITING

    Warsaw, 02-962, Poland

  • SPECDERM Poznanska sp.j.

    RECRUITING

    Bialystok, Podlaskie Voivodeship, 15-375, Poland

  • Shanghai Skin Disease Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200443, China

  • Skin Research of South Florida

    RECRUITING

    Miami, Florida, 33173, United States

  • Skincare Studio

    RECRUITING

    St. John's, Newfoundland and Labrador, A1E 1V4, Canada

  • Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ

    RECRUITING

    Szeged, Csongrád megye, 6720, Hungary

  • Texas Dermatology and Laser Specialists

    RECRUITING

    San Antonio, Texas, 78218, United States

  • The Affiliated Hospital of Hebei University of Engineering

    RECRUITING

    Handan, Hebei, 56029, China

  • The Centre for Dermatology

    RECRUITING

    Richmond Hill, Ontario, L4B 1A5, Canada

  • The First People's Hospital of Hangzhou

    RECRUITING

    Hangzhou, Zhejiang, 310006, China

  • The University of Hong Kong-Shenzhen Hospital

    RECRUITING

    Shenzhen, Guangdong, 518053, China

  • USF Health

    RECRUITING

    Tampa, Florida, 33612, United States

  • UZ Gent

    RECRUITING

    Ghent, Oost-Vlaanderen, 9000, Belgium

  • Universitaetsklinikum Carl Gustav Carus Dresden

    RECRUITING

    Dresden, 01307, Germany

  • Universitaetsklinikum Erlangen

    RECRUITING

    Erlangen, 91054, Germany

  • Universitätsklinikum Münster

    RECRUITING

    Münster, North Rhine-Westphalia, 48149, Germany

  • Wellness Clinical Research

    RECRUITING

    Miami Lakes, Florida, 33016, United States

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