New pill could clear psoriasis in teens
NCT ID NCT06979453
First seen Jun 25, 2026 · Last updated Aug 12, 2026 · Updated 5 times
Summary
This study tests a daily pill called deucravacitinib in teenagers aged 12 to 18 with moderate to severe plaque psoriasis. About 366 participants will receive either the drug or a placebo. The main goals are to see if the drug improves skin clearance by at least 75% and reduces overall severity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Deucravacitinib
- What this could lead to
- If successful, this could provide a new oral treatment option for teenagers with moderate to severe plaque psoriasis, helping clear skin and reduce itching.
- What could go wrong
- This is a phase 3 trial, but results may not apply to all teens. Side effects are possible, and the drug may not work better than placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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"DERMED" Centrum Medyczne Sp. z o.o.
RECRUITINGLodz, 90-265, Poland
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Advanced Medical Research, PC.
RECRUITINGSandy Springs, Georgia, 30328, United States
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Alberta Dermasurgery Centre
RECRUITINGEdmonton, Alberta, T6G 1C3, Canada
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Apex Clinical Research Center
RECRUITINGLorain, Ohio, 44053, United States
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Apex Clinical Research Center
RECRUITINGMayfield Heights, Ohio, 44124, United States
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Apex Clinical Research Center - Canton
RECRUITINGCanton, Ohio, 44716, United States
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Arké SMO S.A de C.V
RECRUITINGVeracruz, 91910, Mexico
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AvantDerm
RECRUITINGToronto, Ontario, M5A 3R6, Canada
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BAG Drs. Med. Quist PartG
RECRUITINGMainz, Rhineland-Palatinate, 55128, Germany
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Beijing Children's hospital, Capital Medical University
RECRUITINGBeijing, Beijing Municipality, 100045, China
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CHUS - Hospital Clinico Universitario
RECRUITINGSantiago de Compostela, 15706, Spain
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CONEXA Investigacion Clinica S.A.
RECRUITINGBuenos Aires, 1012, Argentina
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Center For Dermatology Clinical Research, Inc.
RECRUITINGFremont, California, 94538, United States
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Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman
RECRUITINGLiège, 4000, Belgium
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Centro de Investigaciones Médicas Tucuman
RECRUITINGSAN M. de Tucuman, Tucumán Province, T4000AXL, Argentina
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Centrul de Medicina de Familie
RECRUITINGIași, 700556, Romania
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Chang Gung Medical Foundation-Linkou Branch
RECRUITINGTaoyuan, 333, Taiwan
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Chang Gung Memorial Hospital at Kaohsiung
RECRUITINGKaohsiung Niao Sung Dist, Kaohsiung, 83301, Taiwan
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Charité Universitaetsmedizin Berlin - Campus Mitte
RECRUITINGBerlin, 10117, Germany
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Clinexpert Kft.
RECRUITINGBudapest, Pest County, 1033, Hungary
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Cliniques universitaires Saint-Luc
RECRUITINGBrussels, Bruxelles-Capitale, Région de, 1200, Belgium
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Dawes Fretzin Clinical Research Group, LLC
RECRUITINGIndianapolis, Indiana, 46250, United States
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Debreceni Egyetem Klinikai Kozpont
RECRUITINGDebrecen, 4032, Hungary
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DermEffects
RECRUITINGLondon, Ontario, N6H 5L5, Canada
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Derma Internacional
RECRUITINGBuenos Aires, 1426, Argentina
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Dermatology Affiliates Research Institute
RECRUITINGAtlanta, Georgia, 30305, United States
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Dermatology Research Associates
RECRUITINGLos Angeles, California, 90045, United States
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Dermatology and Skin Cancer Center
RECRUITINGLee's Summit, Missouri, 64064, United States
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Dermatology and Skin Cancer Specialists, LLC
RECRUITINGRockville, Maryland, 20850, United States
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ETYKA Osrodek Badan Klinicznych
RECRUITINGOlsztyn, 10-117, Poland
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore
RECRUITINGRoma, 00168, Italy
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Frontier Derm Partners
RECRUITINGMill Creek, Washington, 98012, United States
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FutureMeds - Targowek
RECRUITINGWarsaw, Masovian Voivodeship, 03-291, Poland
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GCM Medical Group, PSC - Hato Rey Site
RECRUITINGSan Juan, 00917, Puerto Rico
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Golden State Dermatology - Walnut Creek - Ygnacio Valley Road
RECRUITINGWalnut Creek, California, 94598, United States
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Grupo Dermatológico y Estético Pedro Jaén S.A
RECRUITINGMadrid, 28002, Spain
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Guangdong Province Dermatology Hospital
RECRUITINGGuangzhou, Guangdong, 510018, China
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Henry Ford Medical Center
RECRUITINGDetroit, Michigan, 48202-3141, United States
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Hospital Italiano de Buenos Aires
RECRUITINGBuenos Aires, 1181, Argentina
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Hospital Moinhos de Vento
RECRUITINGPorto Alegre, Rio Grande do Sul, 90560-032, Brazil
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Hospital Sant Joan de Déu
RECRUITINGEsplugues de Llobregat, Barcelona [Barcelona], 08950, Spain
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Hospital Universitario 12 de Octubre
RECRUITINGMadrid, 28041, Spain
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Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) - HCFMRP
RECRUITINGRibeirão Preto, São Paulo, 14051-140, Brazil
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Hospital de Niños Dr. Ricardo Gutiérrez
RECRUITINGBuenos Aires, 1425, Argentina
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Hospital de la Santa Creu i Sant Pau
RECRUITINGBarcelona, Catalunya [Cataluña], 08041, Spain
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Hunan Children's Hospital
RECRUITINGChangsha, Hunan, 410007, China
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Instituto Dermatologico de Jalisco
RECRUITINGZapopan, Jalisco, 45190, Mexico
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Instituto de Neumonologia Y Dermatologia
RECRUITINGCiudad Autonoma de Buenos Aires, Buenos Aires, 1425, Argentina
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JDR Dermatology Research
RECRUITINGLas Vegas, Nevada, 89148, United States
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Kaohsiung Veterans General Hospital
RECRUITINGKaohsiung City, 81362, Taiwan
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Kentucky Advanced Medical Research LLC
RECRUITINGMurray, Kentucky, 42071, United States
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Klinika Ambroziak Dermatologia
RECRUITINGWarsaw, 02-953, Poland
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Kuchnir Dermatology & Dermatologic Surgery
RECRUITINGMilford, Massachusetts, 01757, United States
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Life Clinical Trials
RECRUITINGMargate, Florida, 33063, United States
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Local Institution - 0008
NOT_YET_RECRUITINGCaguas, 00725, Puerto Rico
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Local Institution - 0021
NOT_YET_RECRUITINGClearwater, Florida, 33756, United States
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Local Institution - 0025
NOT_YET_RECRUITINGFountain Valley, California, 92708, United States
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Local Institution - 0041
NOT_YET_RECRUITINGBirmingham, Alabama, 35243, United States
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Local Institution - 0045
NOT_YET_RECRUITINGNorfolk, Virginia, 23502, United States
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Local Institution - 0053
ACTIVE_NOT_RECRUITINGPhoenix, Arizona, 85006, United States
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Local Institution - 0077
NOT_YET_RECRUITINGSacramento, California, 95814, United States
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Local Institution - 0095
NOT_YET_RECRUITINGDetroit, Michigan, 48201, United States
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Local Institution - 0124
NOT_YET_RECRUITINGMedellín, Antioquia, 50021, Colombia
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Local Institution - 0125
NOT_YET_RECRUITINGBogota, Cundinamarca, 111 411, Colombia
-
Local Institution - 0137
NOT_YET_RECRUITINGSalvador, Estado de Bahia, 41820-020, Brazil
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Local Institution - 0142
NOT_YET_RECRUITINGMontreal, Quebec, H3T 1C5, Canada
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Local Institution - 0155
NOT_YET_RECRUITINGMonterrey, Nuevo León, 64718, Mexico
-
Local Institution - 0164
NOT_YET_RECRUITINGWinnipeg, Manitoba, R3C 0N2, Canada
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Local Institution - 0166
NOT_YET_RECRUITINGThe Bronx, New York, 10467, United States
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Local Institution - 0167
NOT_YET_RECRUITINGBarranquilla, Atlántico, 080002, Colombia
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Local Institution - 0170
NOT_YET_RECRUITINGSão Paulo, 05403-000, Brazil
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Local Institution - 0174
WITHDRAWNBucharest, Bucharest, 020125, Romania
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Local Institution - 0177
WITHDRAWNLublin, Lublin Voivodeship, 20-573, Poland
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Local Institution - 0182
NOT_YET_RECRUITINGPorto Alegre, Rio Grande do Sul, 90035-903, Brazil
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Local Institution - 0187
NOT_YET_RECRUITINGRome, Lazio, 00133, Italy
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Local Institution - 0202
NOT_YET_RECRUITINGMetairie, Louisiana, 70001, United States
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Local Institution - 0205
NOT_YET_RECRUITINGNew York, New York, 10075, United States
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Local Institution - 0210
WITHDRAWNBrussels, Bruxelles-Capitale, Région de, 1200, Belgium
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Local Institution - 0213
WITHDRAWNBucharest, Bucharest, 30463, Romania
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Local Institution - 0225
NOT_YET_RECRUITINGMedellín, Antioquia, 050012, Colombia
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Local Institution - 0228
NOT_YET_RECRUITINGChengdu, Sichuan, 610091, China
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Local Institution - 0233
NOT_YET_RECRUITINGColumbia, Missouri, 65201, United States
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Local Institution - 0234
COMPLETEDHickory, North Carolina, 28602, United States
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Local Institution - 0240
NOT_YET_RECRUITINGToronto, Ontario, M5G 1X8, Canada
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Local Institution - 0248
COMPLETEDNashville, Tennessee, 37205, United States
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Local Institution - 0253
NOT_YET_RECRUITINGMexico City, Mexico City, 06720, Mexico
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Local Institution - 0254
NOT_YET_RECRUITINGBayamón, 00960, Puerto Rico
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Local Institution - 0257
NOT_YET_RECRUITINGMérida, 97070, Mexico
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Local Institution - 0258
NOT_YET_RECRUITINGToluca, 50010, Mexico
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Local Institution - 0259
NOT_YET_RECRUITINGChihuahua City, 31217, Mexico
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Local Institution - 0261
NOT_YET_RECRUITINGBirmingham, Alabama, 35203, United States
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Local Institution - 0264
NOT_YET_RECRUITINGSpokane, Washington, 99204, United States
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Local Institution - 0265
NOT_YET_RECRUITINGJinan, Shandong, 250022, China
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Local Institution - 0271
NOT_YET_RECRUITINGAmmon, Idaho, 83406, United States
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Local Institution - 0273
NOT_YET_RECRUITINGBrooklyn, New York, 11203, United States
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Local Institution - 0278
NOT_YET_RECRUITINGColumbia, Missouri, 65212, United States
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Local Institution - 0280
NOT_YET_RECRUITINGSouthlake, Texas, 76092, United States
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Local Institution - 0281
NOT_YET_RECRUITINGRobbinsville, New Jersey, 08691, United States
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Local Institution - 0282
NOT_YET_RECRUITINGGdansk, Pomeranian Voivodeship, 80-546, Poland
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Local Institution - 0283
NOT_YET_RECRUITINGClifton, New Jersey, 07013, United States
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Local Institution - 0284
NOT_YET_RECRUITINGCampinas, São Paulo, 13086-888, Brazil
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Local Institution - 0285
NOT_YET_RECRUITINGBucharest, Bucharest, 030463, Romania
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Local Institution - 0286
NOT_YET_RECRUITINGCluj-Napoca, 400006, Romania
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Lotus-Med Tunari
RECRUITINGBucharest, Bucharest, 020528, Romania
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MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research
RECRUITINGTampa, Florida, 33607, United States
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National Taiwan University Hospital
RECRUITINGTaipei, 10002, Taiwan
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New Derm Clinical SRL
RECRUITINGTimișoara, 300757, Romania
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Northridge Clinical Trials
RECRUITINGNorthridge, California, 91325, United States
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ObjectiveHealth - Goodlettsville Dermatology Research
RECRUITINGGoodlettsville, Tennessee, 37072, United States
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Paddington Testing Company
RECRUITINGPhiladelphia, Pennsylvania, 19103, United States
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Paradigm Clinical Research, LLC
RECRUITINGWheat Ridge, Colorado, 80033, United States
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Peking University Third Hospital
RECRUITINGBeijing, Beijing Municipality, 100091, China
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People's Hospital of Henan Province
RECRUITINGZhengzhou, Henan, 450003, China
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Policlinica Providența
RECRUITINGIași, 700259, Romania
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Psoriahue
RECRUITINGCiudad Autonoma de Buenos Aires, Buenos Aires, C1425DKG, Argentina
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Royalderm Agnieszka Nawrocka
RECRUITINGWarsaw, 02-962, Poland
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SPECDERM Poznanska sp.j.
RECRUITINGBialystok, Podlaskie Voivodeship, 15-375, Poland
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Shanghai Skin Disease Hospital
RECRUITINGShanghai, Shanghai Municipality, 200443, China
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Skin Research of South Florida
RECRUITINGMiami, Florida, 33173, United States
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Skincare Studio
RECRUITINGSt. John's, Newfoundland and Labrador, A1E 1V4, Canada
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Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ
RECRUITINGSzeged, Csongrád megye, 6720, Hungary
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Texas Dermatology and Laser Specialists
RECRUITINGSan Antonio, Texas, 78218, United States
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The Affiliated Hospital of Hebei University of Engineering
RECRUITINGHandan, Hebei, 56029, China
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The Centre for Dermatology
RECRUITINGRichmond Hill, Ontario, L4B 1A5, Canada
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The First People's Hospital of Hangzhou
RECRUITINGHangzhou, Zhejiang, 310006, China
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The University of Hong Kong-Shenzhen Hospital
RECRUITINGShenzhen, Guangdong, 518053, China
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USF Health
RECRUITINGTampa, Florida, 33612, United States
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UZ Gent
RECRUITINGGhent, Oost-Vlaanderen, 9000, Belgium
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Universitaetsklinikum Carl Gustav Carus Dresden
RECRUITINGDresden, 01307, Germany
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Universitaetsklinikum Erlangen
RECRUITINGErlangen, 91054, Germany
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Universitätsklinikum Münster
RECRUITINGMünster, North Rhine-Westphalia, 48149, Germany
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Wellness Clinical Research
RECRUITINGMiami Lakes, Florida, 33016, United States
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