New pill could help kids with severe psoriasis

NCT ID NCT04772079

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a drug called deucravacitinib in children and teens aged 4 to 18 with moderate to severe plaque psoriasis. The trial will measure how the drug works in the body, how well it clears psoriasis, and its safety over up to 5 years. Participants are randomly assigned to receive either the drug or a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Deucravacitinib (a pill that targets the immune system to reduce inflammation)
What this could lead to: If successful, this could provide a new oral treatment option for children and teens with moderate to severe plaque psoriasis, potentially improving skin clearance and quality of life.
What could go wrong: This is still an early-stage pediatric study (Phase 3) with a small number of participants (153). The drug may not work as well in children as in adults, and long-term safety, including effects on growth and development, is still being studied.

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Conditions

The condition(s) this trial relates to.

psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PLAQUE PSORIASIS

Contacts and locations

Locations

Alberta Dermasurgery Centre
RECRUITING

Edmonton, Alberta, T6G 1C3, Canada
Arké SMO S.A de C.V
RECRUITING

Veracruz, 91910, Mexico
CCBR Clinical Research
RECRUITING

Bucharest, Bucharest, 30463, Romania
CONEXA Investigacion Clinica S.A.
RECRUITING

Buenos Aires, 1012, Argentina
Centre Hospitalier Universitaire Dijon Bourgogne - Hôpital François Mitterrand-dermatology
RECRUITING

Dijon, 21000, France
Centre Hospitalier Universitaire de Nice - Hôpital l'Archet
RECRUITING

Nice, 06202, France
Centre Hospitalier de Calais
RECRUITING

Calais, 62107, France
Centro de Investigaciones Metabólicas (CINME)
RECRUITING

Buenos Aires, C1056ABI, Argentina
Centro de Pesquisas da Clínica IBIS
RECRUITING

Salvador, Estado de Bahia, 41820-020, Brazil
Charité Universitaetsmedizin Berlin - Campus Mitte
RECRUITING

Berlin, 10117, Germany
Consultora Integral de Salud
RECRUITING

Córdoba, 5004, Argentina
Crea de Guadalajara
RECRUITING

Guadalajara, Jalisco, 44600, Mexico
Dermoklinika Centrum Medyczne S.C. M. Kierstan, J. Narbutt, A. Lesiak
RECRUITING

Lodz, 90-436, Poland
Fukuoka University Hospital
RECRUITING

Fukuoka, Jonan-Ku, Fukuoka, 814-0180, Japan
Grupo Clínico CATEI S.C.
RECRUITING

Guadalajara, Jalisco, 44638, Mexico
Hospital General Universitario de Alicante-Dermatology
RECRUITING

Alicante, 03010, Spain
Hospital Italiano de Buenos Aires
RECRUITING

CABA, 1199, Argentina
Hospital Moinhos de Vento
RECRUITING

Porto Alegre, Rio Grande do Sul, 90560-032, Brazil
Hospital Sant Joan de Déu-URC Dermatology
RECRUITING

Esplugues de Llobregat, 08950, Spain
Hospital Universitario 12 de Octubre-DERMATOLOGY
RECRUITING

Madrid, 28041, Spain
Hospital Universitario La Paz-UCICEC/DERMA
RECRUITING

Madrid, 28046, Spain
Hospital Universitario de Gran Canaria Doctor Negrín-Dermatología
RECRUITING

Las Palmas de GC, 35019, Spain
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) - HCFMRP
RECRUITING

Ribeirão Preto, São Paulo, 14051-140, Brazil
Instituto de Neumonologia Y Dermatologia
RECRUITING

Ciudad Autonoma de Buenos Aires, Buenos Aires, 1425, Argentina
Kath. Kinderkrankenhaus Wilhelmstift
RECRUITING

Hamburg, 22149, Germany
Local Institution - 0001
COMPLETED

Melbourne, Victoria, 3995, Australia
Local Institution - 0002
WITHDRAWN

Westmead, New South Wales, 2145, Australia
Local Institution - 0010
COMPLETED

Calgary, Alberta, T2J 7E1, Canada
Local Institution - 0011
COMPLETED

Krakow, 30-438, Poland
Local Institution - 0021
COMPLETED

Paris, 75019, France
Local Institution - 0039
WITHDRAWN

Hamilton, Ontario, L8N 1Y2, Canada
Local Institution - 0040
WITHDRAWN

Isehara, Kanagawa, 259-1193, Japan
Local Institution - 0047
COMPLETED

Seoul, Seoul-teukbyeolsi [Seoul], 03722, South Korea
Local Institution - 0048
COMPLETED

Seoul, Seoul-teukbyeolsi [Seoul], 02447, South Korea
Local Institution - 0067
WITHDRAWN

São Paulo, 05403-000, Brazil
Local Institution - 0080
WITHDRAWN

Bucharest, Bucharest, 012292, Romania
Local Institution - 0081
WITHDRAWN

Bucharest, Bucharest, 020125, Romania
Local Institution - 0083
NOT_YET_RECRUITING

Rio de Janeiro, 22470-220, Brazil
Local Institution - 0088
WITHDRAWN

Bucharest, Bucharest, 020762, Romania
Lotus-Med Tunari
RECRUITING

Bucharest, 020528, Romania
Lynderm Research Inc.
RECRUITING

Markham, Ontario, L3P 1X3, Canada
Mie University Hospital
RECRUITING

Tsu, Mie-ken, 514-8507, Japan
Monash Health
RECRUITING

Clayton, Victoria, 3168, Australia
Mounts Bay Medical
RECRUITING

Connor Downs, TR27 5DT, United Kingdom
Nagoya City University Hospital
RECRUITING

Nagoya, Aichi-ken, 467-8602, Japan
Nippon Life Hospital
RECRUITING

Osaka, 550-0006, Japan
OSI Ezkerraldea-Enkarterri-Cruces - Hospital Universitario Cruces-Dermatology
RECRUITING

Barakaldo, 48903, Spain
Państwowy Instytut Medyczny MSWiA-Klinika Dermatologii
RECRUITING

Warsaw, 02-507, Poland
Psoriahue
RECRUITING

Ciudad Autonoma de Buenos Aires, Buenos Aires, C1425DKG, Argentina
Queensland Children's Hospital
RECRUITING

Brisbane, Queensland, 4101, Australia
RM Pharma Specialists
RECRUITING

Mexico City, Mexico City, 03100, Mexico
Spitalul Clinic Judetean Mures
RECRUITING

Târgu Mureş, 540342, Romania
Spitalul clinic de urgenta pentru copii Sf. Maria
RECRUITING

Iași, 700309, Romania
Teikyo University Hospital
RECRUITING

Itabashi-ku, Tokyo, 173-8606, Japan
The Catholic Univ. of Korea Seoul St. Mary's Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [Seoul], 06591, South Korea
The Hospital for Sick Children
RECRUITING

Toronto, Ontario, M5G 1X8, Canada
The Skin Hospital
RECRUITING

Darlinghurst, New South Wales, 2010, Australia
Tokyo Medical University Hospital
RECRUITING

Shinjuku-ku, Tokyo, 160-0023, Japan
Universitaetsklinikum Carl Gustav Carus Dresden
RECRUITING

Dresden, Saxony, 01307, Germany
Universitätsklinikum Münster
RECRUITING

Münster, North Rhine-Westphalia, 48149, Germany
Universitätsmedizin Johannes Gutenberg Universität Mainz
RECRUITING

Mainz, Rhineland-Palatinate, 55131, Germany
Veracity Clinical Research
RECRUITING

Woolloongabba, Queensland, 4102, Australia
WroMedica
RECRUITING

Wroclaw, 51-620, Poland

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