New pill aims to tame the flames of lupus

NCT ID NCT05617677

Ongoing Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an oral medication called deucravacitinib can better control symptoms of active, moderate-to-severe lupus compared to a placebo. It involves 516 adults who will take the pill alongside their current lupus medications. The main goal is to see if it reduces overall disease activity and improves specific symptoms like skin rashes and joint pain.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Kaiser Permanente

Fontana, California, 92335, United States
Lake Cumberland Rheumatology

New Albany, Indiana, 47150, United States
Local Institution - 0002

Tamarac, Florida, 33321, United States
Local Institution - 0003

Memphis, Tennessee, 38119, United States
Local Institution - 0005

The Woodlands, Texas, 77382, United States
Local Institution - 0006

Detroit, Michigan, 48202, United States
Local Institution - 0007

Orlando, Florida, 32806, United States
Local Institution - 0009

Roanoke, Virginia, 24016, United States
Local Institution - 0010

Gainesville, Florida, 32610, United States
Local Institution - 0011

Seattle, Washington, 98122, United States
Local Institution - 0012

Birmingham, Alabama, 35205, United States
Local Institution - 0013

Buenos Aires, Buenos Aires F.D., C1121ABE, Argentina
Local Institution - 0015

Mexicali, Estado de Baja California, 21100, Mexico
Local Institution - 0016

Mexico City, Mexico City, 06700, Mexico
Local Institution - 0017

Mendoza, 5500, Argentina
Local Institution - 0018

Chihuahua City, 31000, Mexico
Local Institution - 0020

CABA, Buenos Aires F.D., 1406, Argentina
Local Institution - 0021

Zhuzhou, Hunan, 412007, China
Local Institution - 0022

Buenos Aires, C1221ADC, Argentina
Local Institution - 0023

Zhengzhou, Henan, 450000, China
Local Institution - 0024

Zapopan, Jalisco, 45116, Mexico
Local Institution - 0026

Mexico City, Mexico City, 01120, Mexico
Local Institution - 0027

Mexico City, Mexico City, 03720, Mexico
Local Institution - 0028

Pingxiang, Jiangxi, 337055, China
Local Institution - 0029

Guangzhou, Guangdong, 510000, China
Local Institution - 0031

Jiujiang, Jiangxi, 332000, China
Local Institution - 0032

Buenos Aires, 1123, Argentina
Local Institution - 0033

Krakow, Lesser Poland Voivodeship, 30-363, Poland
Local Institution - 0034

Nadarzyn, Masovian Voivodeship, 05-830, Poland
Local Institution - 0035

Bialystok, 15-707, Poland
Local Institution - 0036

Poznan, Greater Poland Voivodeship, 60-218, Poland
Local Institution - 0037

Shenzhen, Guangdong, 518020, China
Local Institution - 0039

Shenyang, Liaoning, 110001, China
Local Institution - 0040

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-168, Poland
Local Institution - 0041

Juiz de Fora, Minas Gerais, 36010-570, Brazil
Local Institution - 0042

Belo Horizonte, Minas Gerais, 30150-221, Brazil
Local Institution - 0043

Ürümqi, Xinjiang, 830001, China
Local Institution - 0044

Changsha, Hunan, 410008, China
Local Institution - 0045

Shanghai, Shanghai Municipality, 200040, China
Local Institution - 0047

Katowice, Silesian Voivodeship, 40-081, Poland
Local Institution - 0049

Shanghai, Shanghai Municipality, 200127, China
Local Institution - 0050

Mexico City, Mexico City, 06700, Mexico
Local Institution - 0051

Guangzhou, Guangdong, 510080, China
Local Institution - 0053

Tianjin, Tianjin Municipality, 300052, China
Local Institution - 0054

New Haven, Connecticut, 06510, United States
Local Institution - 0056

Barranquilla, Atlántico, 080002, Colombia
Local Institution - 0057

Chía, 250001, Colombia
Local Institution - 0060

Pisa, Tuscany, 56126, Italy
Local Institution - 0061

Cologne, 50937, Germany
Local Institution - 0063

Franklin, Wisconsin, 53132, United States
Local Institution - 0064

Allen, Texas, 75013, United States
Local Institution - 0065

Dallas, Texas, 75390, United States
Local Institution - 0066

São José do Rio Preto, São Paulo, 15090000, Brazil
Local Institution - 0067

Tuenmen, 999077, Hong Kong
Local Institution - 0068

Nantes, Loire-Atlantique, 44093 Cedex 1, France
Local Institution - 0069

Brescia, 25123, Italy
Local Institution - 0070

Beijing, Beijing Municipality, 100730, China
Local Institution - 0071

Nanchang, Jiangxi, 330006, China
Local Institution - 0072

Milan, 20132, Italy
Local Institution - 0076

Bucharest, București, 011172, Romania
Local Institution - 0077

Schaumburg, Illinois, 60195, United States
Local Institution - 0078

Quilmes, Buenos Aires, 1878, Argentina
Local Institution - 0079

Shanghai, Shanghai Municipality, 200025, China
Local Institution - 0080

Guangzhou, Guangdong, 510120, China
Local Institution - 0082

León, Guanajuato, 37000, Mexico
Local Institution - 0083

Puebla City, 72160, Mexico
Local Institution - 0084

Rome, Lazio, 00161, Italy
Local Institution - 0085

New York, New York, 10016, United States
Local Institution - 0086

Bucaramanga, Santander Department, 680003, Colombia
Local Institution - 0087

Miami, Florida, 33136, United States
Local Institution - 0088

Fort Worth, Texas, 76177, United States
Local Institution - 0089

Hohhot, Inner Mongolia, 010050, China
Local Institution - 0090

La Palma, California, 90623, United States
Local Institution - 0092

Shenyang, Liaoning, 110004, China
Local Institution - 0093

Cali, 760035, Colombia
Local Institution - 0094

Râmnicu Vâlcea, Vâlcea County, 247065, Romania
Local Institution - 0095

Milan, Lombardy, 20122, Italy
Local Institution - 0096

Lago Sul, Federal District, 71635580, Brazil
Local Institution - 0097

Padua, Veneto, 35128, Italy
Local Institution - 0098

Rochester, New York, 14642, United States
Local Institution - 0099

Denver, Colorado, 80230, United States
Local Institution - 0100

Bogotá, 110221, Colombia
Local Institution - 0101

Suwon, Kyǒnggi-do, 16499, South Korea
Local Institution - 0102

Gwangju, Kwangju-Kwangyǒkshi, 61469, South Korea
Local Institution - 0103

Lima, 33, Peru
Local Institution - 0104

Lima, 15046, Peru
Local Institution - 0107

Xiamen, Fujian, 361003, China
Local Institution - 0108

Indianapolis, Indiana, 46202, United States
Local Institution - 0109

Tübingen, Baden-Wurttemberg, 72076, Germany
Local Institution - 0110

Bengbu, Anhui, 233017, China
Local Institution - 0111

Planegg, 82152, Germany
Local Institution - 0112

Mexico City, Mexico City, 14080, Mexico
Local Institution - 0114

London, Ontario, N6A 4V2, Canada
Local Institution - 0115

Toronto, Ontario, M5T 2S8, Canada
Local Institution - 0116

Chengdu, Sichuan, 610041, China
Local Institution - 0117

Nanchang, Jiangxi, 330006, China
Local Institution - 0119

Manorhamilton, Leitrim, 0, Ireland
Local Institution - 0120

Erlangen, 91054, Germany
Local Institution - 0122

Lima, 15047, Peru
Local Institution - 0123

San Miguel de Tucumán, Tucumán Province, 4000, Argentina
Local Institution - 0124

Los Angeles, California, 90095, United States
Local Institution - 0125

São Paulo, 05403-000, Brazil
Local Institution - 0126

Calgary, Alberta, T2N 4N1, Canada
Local Institution - 0128

Santa Barbara, California, 93108, United States
Local Institution - 0129

Changzhou, Jiangsu, 213003, China
Local Institution - 0130

Cork, T12 E8YV, Ireland
Local Institution - 0132

Hangzhou, Zhejiang, 310003, China
Local Institution - 0133

Luoyang, Henan, 471003, China
Local Institution - 0135

Wenzhou, Zhejiang, 325000, China
Local Institution - 0136

Rimouski, Quebec, G5L 5T1, Canada
Local Institution - 0137

Wuhan, Hubei, 430022, China
Local Institution - 0138

Córdoba, 5004, Argentina
Local Institution - 0139

Seattle, Washington, 98195, United States
Local Institution - 0140

Buenos Aires, CP1280AEB, Argentina
Local Institution - 0141

Bucharest, București, 020125, Romania
Local Institution - 0142

Craiova, Dolj, 200347, Romania
Local Institution - 0143

Timișoara, 300766, Romania
Local Institution - 0144

Seoul, Seoul-teukbyeolsi [Seoul], 06591, South Korea
Local Institution - 0146

Dresden, Saxony, 01307, Germany
Local Institution - 0147

Lawrenceville, Georgia, 30046, United States
Local Institution - 0148

Bucharest, București, 011053, Romania
Local Institution - 0149

Jinan, Shandong, 250001, China
Local Institution - 0150

Strasbourg, Alsace, 67091, France
Local Institution - 0151

Lübeck, Schleswig-Holstein, 23538, Germany
Local Institution - 0152

Bucharest, București, 014142, Romania
Local Institution - 0153

Baoding, Hebei, 071030, China
Local Institution - 0154

Naples, 80131, Italy
Local Institution - 0155

Charlotte, North Carolina, 28211, United States
Local Institution - 0156

Tours, 37032, France
Local Institution - 0157

Dublin, D08 E9P6, Ireland
Local Institution - 0158

Taiyuan, 030032, China
Local Institution - 0159

The Bronx, New York, 10467, United States
Local Institution - 0160

Hamilton, Ontario, L8S 4K1, Canada
Local Institution - 0161

Verona, 37134, Italy
Local Institution - 0162

Sofia, 1784, Bulgaria
Local Institution - 0163

Plovdiv, 4000, Bulgaria
Local Institution - 0164

Warsaw, Masovian Voivodeship, 02-118, Poland
Local Institution - 0165

Tampa, Florida, 33614, United States
Local Institution - 0166

Warsaw, Masovian Voivodeship, 02-637, Poland
Local Institution - 0167

Kaunas, Kaunas County, LT-50161, Lithuania
Local Institution - 0168

Istanbul, 34098, Turkey (Türkiye)
Local Institution - 0169

Seoul, 04763, South Korea
Local Institution - 0170

Bogotá, 110231, Colombia
Local Institution - 0172

Dublin, D15 X40D, Ireland
Local Institution - 0173

Le Kremlin-Bicêtre, 94270, France
Local Institution - 0174

Medellín, Antioquia, 050021, Colombia
Local Institution - 0176

Munich, Bavaria, 80336, Germany
Local Institution - 0177

Summit, New Jersey, 07901, United States
Local Institution - 0179

Eagan, Minnesota, 55121, United States
Local Institution - 0180

Manhasset, New York, 11030, United States
Local Institution - 0181

Porto Alegre, Rio Grande do Sul, 90610000, Brazil
Local Institution - 0184

Ankara, 06560, Turkey (Türkiye)
Local Institution - 0185

Campinas, São Paulo, 13015-001, Brazil
Local Institution - 0186

Rio de Janeiro, 20551-030, Brazil
Local Institution - 0187

Ribeirão Preto, São Paulo, 14051-140, Brazil
Local Institution - 0189

Kocaeli, 41380, Turkey (Türkiye)
Local Institution - 0190

Curitiba, Paraná, 80730-150, Brazil
Local Institution - 0191

São Paulo, São Paulo, 04038-002, Brazil
Local Institution - 0193

Tucson, Arizona, 85724, United States
Local Institution - 0195

Chemnitz, 09117, Germany
Local Institution - 0197

San Juan, 00917, Puerto Rico
Local Institution - 0199

Arequipa, 05154, Peru
Local Institution - 0200

Ahmedabad, Gujarat, 380015, India
Local Institution - 0202

Bengaluru, Karnataka, 560010, India
Local Institution - 0203

Caguas, 00725, Puerto Rico
Local Institution - 0204

Atlanta, Georgia, 30318, United States
Local Institution - 0205

Hyderabad, Telangana, 500082, India
Local Institution - 0208

Gurugram, Haryana, 122001, India
Local Institution - 0210

Bucharest, București, 30463, Romania
Local Institution - 0211

Bełchatów, Łódź Voivodeship, 97-400, Poland
Local Institution - 0212

Poznan, 60-702, Poland
Local Institution - 0213

Vizianagaram, Andhra Pradesh, 0, India
Local Institution - 0215

Bucharest, București, 041303, Romania
Local Institution - 0216

Iași, Iaşi, 700127, Romania
Local Institution - 0217

Sofia, 1407, Bulgaria
Local Institution - 0219

Lubbock, Texas, 79415, United States
Local Institution - 0220

Nanchang, Jiangxi, 330006, China
Local Institution - 0222

Hyderabad, Telangana, 500038, India
Local Institution - 0224

Salvador, Estado de Bahia, 40150-150, Brazil
Local Institution - 0225

New Orleans, Louisiana, 70121, United States
Local Institution - 0227

Morton Grove, Illinois, 60053, United States
Local Institution - 0228

Lawrenceville, Georgia, 30044, United States
Local Institution - 0229

Phoenix, Arizona, 85006, United States
Local Institution - 0236

Chisinau, 2025, Moldova
Local Institution - 0238

Chisinau, Chișinău, MD-2051, Moldova
Local Institution - 0240

Buenos Aires, C1023AAB, Argentina
Local Institution - 0242

Plantation, Florida, 33317, United States
Local Institution - 0243

Surat, Gujarat, 395010, India
Local Institution - 0245

Charlotte, North Carolina, 28207, United States
Local Institution - 0246

Summerville, South Carolina, 29486, United States
Local Institution - 0247

La Mesa, California, 91942, United States
Local Institution - 0248

Sacramento, California, 95817, United States
Local Institution - 0249

Coral Springs, Florida, 33065, United States
Local Institution - 0250

Houston, Texas, 77090, United States
Local Institution - 0252

San Juan, 00909, Puerto Rico
Local Institution - 0253

San Diego, California, 92128, United States
Velocity Clinical Research, Lublin

Lublin, 20-362, Poland

Conditions

Explore the condition pages connected to this study.

SYSTEMIC LUPUS ERYTHEMATOSUS