New hope for kids with arthritis: experimental drug enters final testing phase

NCT ID NCT06869551

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called deucravacitinib in children aged 5 to 17 with active juvenile psoriatic arthritis, a condition causing joint pain and swelling. The trial aims to see if the drug can control the disease and prevent flare-ups. About 60 participants will receive either the drug or a placebo, and researchers will monitor safety and drug levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Deucravacitinib

What this could lead to

If successful, this could provide a new treatment option for children with juvenile psoriatic arthritis who haven't responded to other medications.

What could go wrong

This is a relatively small trial (60 participants), and the drug may not work better than placebo or could cause side effects. Results may not apply to all children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

juvenile idiopathic arthritis psoriasis-related juvenile idiopathic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Azienda Ospedaliera Universitaria Meyer IRCCS

    RECRUITING

    Florence, Tuscany, 50139, Italy

    Contact Phone: •••-•••-••••

  • Centro de Oncologia Leonardo Da Vinci - ATO Terapias

    RECRUITING

    Fortaleza, Ceará, 60140-025, Brazil

    Contact Phone: •••-•••-••••

  • Children's Hospital of Fudan University

    RECRUITING

    Shanghai, 201102, China

    Contact Phone: •••-•••-••••

  • Childrens Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, 210008, China

    Contact Phone: •••-•••-••••

  • Fakultni nemocnice Olomouc

    RECRUITING

    Olomouc, Olomouc Region, 779 00, Czechia

    Contact Phone: •••-•••-••••

  • Fakultni nemocnice v Motole

    RECRUITING

    Prague, Praha 5, 150 06, Czechia

    Contact Phone: •••-•••-••••

  • Guangzhou Women and Children's Medical Center

    RECRUITING

    Guangzhou, Guangdong, 510000, China

    Contact Phone: •••-•••-••••

  • Hospital Das Clinicas Ufpe

    RECRUITING

    Recife, Pernambuco, 50670-420, Brazil

    Contact Phone: •••-•••-••••

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, Barcelona [Barcelona], 08035, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitari i Politecnic La Fe

    RECRUITING

    Valencia, 46026, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitario Ramón y Cajal

    RECRUITING

    Madrid, Madrid, Comunidad de, 28034, Spain

    Contact Phone: •••-•••-••••

  • Istanbul Universitesi Cerrahpasa

    RECRUITING

    Istanbul- Fatih, Istanbul, 34098, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • Kinderklinik des Uni-Klinikums Erlangen

    RECRUITING

    Erlangen, 91054, Germany

    Contact Phone: •••-•••-••••

  • LMK Serviços Médicos S/S

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90480-000, Brazil

    Contact Phone: •••-•••-••••

  • Local Institution - 0010

    WITHDRAWN

    São Paulo, 04022-001, Brazil

  • Local Institution - 0013

    WITHDRAWN

    Curitiba, Paraná, 80250-060, Brazil

  • Local Institution - 0017

    WITHDRAWN

    San Juan, 00917, Puerto Rico

  • Local Institution - 0020

    WITHDRAWN

    Chicago, Illinois, 60611, United States

  • Local Institution - 0023

    WITHDRAWN

    Indianapolis, Indiana, 46202, United States

  • Local Institution - 0027

    NOT_YET_RECRUITING

    Rio de Janeiro, 21941-612, Brazil

    Contact

  • Local Institution - 0032

    WITHDRAWN

    Cuiabá, Mato Grosso, 78020-500, Brazil

  • Local Institution - 0033

    WITHDRAWN

    Porto Alegre, Rio Grande do Sul, 90020-090, Brazil

  • Local Institution - 0036

    WITHDRAWN

    Austin, Texas, 78723, United States

  • Local Institution - 0038

    WITHDRAWN

    Lancaster, California, 93534, United States

  • Local Institution - 0044

    NOT_YET_RECRUITING

    Ankara, 06230, Turkey (Türkiye)

    Contact

  • Local Institution - 0048

    WITHDRAWN

    Iași, Iaşi, 700135, Romania

  • Local Institution - 0049

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100045, China

    Contact

  • Local Institution - 0059

    WITHDRAWN

    North New Hyde Park, New York, 11040, United States

  • Local Institution - 0061

    NOT_YET_RECRUITING

    Ankara, 06170, Turkey (Türkiye)

    Contact

  • Local Institution - 0062

    WITHDRAWN

    Sofia, 1797, Bulgaria

  • Local Institution - 0065

    WITHDRAWN

    Cincinnati, Ohio, 45229, United States

  • Local Institution - 0066

    WITHDRAWN

    Cleveland, Ohio, 44109, United States

  • Local Institution - 0069

    NOT_YET_RECRUITING

    Sofia, 1309, Bulgaria

    Contact

  • Local Institution - 0072

    NOT_YET_RECRUITING

    Curitiba, Paraná, 80250-060, Brazil

    Contact

  • Local Institution - 0073

    NOT_YET_RECRUITING

    Vila Clementino, São Paulo-SP, 04038-002, Brazil

    Contact

  • Local Institution - 0074

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100020, China

    Contact

  • Praxis Kinder- und Jugendrheumatologie Dr. Ivan Foeldvari

    RECRUITING

    Hamburg, 22081, Germany

    Contact Phone: •••-•••-••••

  • Santa Casa Instituto de Pesquisa

    RECRUITING

    São Paulo, 01223-001, Brazil

    Contact Phone: •••-•••-••••

  • Santa Casa de Misericordia de Belo Horizonte

    RECRUITING

    Belo Horizonte, Minas Gerais, 30150-221, Brazil

    Contact Phone: •••-•••-••••

  • Sc Medaudio-Optica Srl

    RECRUITING

    Râmnicu Vâlcea, Vâlcea County, 247065, Romania

    Contact Phone: •••-•••-••••

  • Spitalul Clinic de Urgenta pentru Copii Cluj-Napoca

    RECRUITING

    Cluj-Napoca, Cluj, 400177, Romania

    Contact Phone: •••-•••-••••

  • The Children's Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, Chongqing Municipality, 400065, China

    Contact Phone: •••-•••-••••

  • The Children's Hospital of Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310057, China

    Contact Phone: •••-•••-••••

  • The First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130000, China

    Contact Phone: •••-•••-••••

  • Umraniye Training and Research Hospital

    RECRUITING

    Istanbul, 34766, Turkey (Türkiye)

    Contact Phone: •••-•••-••••

  • University Multiprofile Hospital for Active Treatment "Sveti Georgi" EAD

    RECRUITING

    Plovdiv, 4002, Bulgaria

    Contact Phone: •••-•••-••••

  • University of Naples Federico II

    RECRUITING

    Naples, Campania, 80131, Italy

    Contact Phone: •••-•••-••••