New hope for kids with arthritis: experimental drug enters final testing phase

NCT ID NCT06869551

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called deucravacitinib in children aged 5 to 17 with active juvenile psoriatic arthritis, a condition causing joint pain and swelling. The trial aims to see if the drug can control the disease and prevent flare-ups. About 60 participants will receive either the drug or a placebo, and researchers will monitor safety and drug levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Deucravacitinib
What this could lead to: If successful, this could provide a new treatment option for children with juvenile psoriatic arthritis who haven't responded to other medications.
What could go wrong: This is a relatively small trial (60 participants), and the drug may not work better than placebo or could cause side effects. Results may not apply to all children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

juvenile idiopathic arthritis psoriasis-related juvenile idiopathic arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

JUVENILE PSORIATIC ARTHRITIS

Contacts and locations

Locations

Azienda Ospedaliera Universitaria Meyer IRCCS
RECRUITING

Florence, Tuscany, 50139, Italy
Centro de Oncologia Leonardo Da Vinci - ATO Terapias
RECRUITING

Fortaleza, Ceará, 60140-025, Brazil
Children's Hospital of Fudan University
RECRUITING

Shanghai, 201102, China
Childrens Hospital of Nanjing Medical University
RECRUITING

Nanjing, Jiangsu, 210008, China
Fakultni nemocnice Olomouc
RECRUITING

Olomouc, Olomouc Region, 779 00, Czechia
Fakultni nemocnice v Motole
RECRUITING

Prague, Praha 5, 150 06, Czechia
Guangzhou Women and Children's Medical Center
RECRUITING

Guangzhou, Guangdong, 510000, China
Hospital Das Clinicas Ufpe
RECRUITING

Recife, Pernambuco, 50670-420, Brazil
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, Barcelona [Barcelona], 08035, Spain
Hospital Universitari i Politecnic La Fe
RECRUITING

Valencia, 46026, Spain
Hospital Universitario Ramón y Cajal
RECRUITING

Madrid, Madrid, Comunidad de, 28034, Spain
Istanbul Universitesi Cerrahpasa
RECRUITING

Istanbul- Fatih, Istanbul, 34098, Turkey (Türkiye)
Kinderklinik des Uni-Klinikums Erlangen
RECRUITING

Erlangen, 91054, Germany
LMK Serviços Médicos S/S
RECRUITING

Porto Alegre, Rio Grande do Sul, 90480-000, Brazil
Local Institution - 0010
WITHDRAWN

São Paulo, 04022-001, Brazil
Local Institution - 0013
WITHDRAWN

Curitiba, Paraná, 80250-060, Brazil
Local Institution - 0017
WITHDRAWN

San Juan, 00917, Puerto Rico
Local Institution - 0020
WITHDRAWN

Chicago, Illinois, 60611, United States
Local Institution - 0023
WITHDRAWN

Indianapolis, Indiana, 46202, United States
Local Institution - 0027
NOT_YET_RECRUITING

Rio de Janeiro, 21941-612, Brazil
Local Institution - 0032
WITHDRAWN

Cuiabá, Mato Grosso, 78020-500, Brazil
Local Institution - 0033
WITHDRAWN

Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
Local Institution - 0036
WITHDRAWN

Austin, Texas, 78723, United States
Local Institution - 0038
WITHDRAWN

Lancaster, California, 93534, United States
Local Institution - 0044
NOT_YET_RECRUITING

Ankara, 06230, Turkey (Türkiye)
Local Institution - 0048
WITHDRAWN

Iași, Iaşi, 700135, Romania
Local Institution - 0049
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100045, China
Local Institution - 0059
WITHDRAWN

North New Hyde Park, New York, 11040, United States
Local Institution - 0061
NOT_YET_RECRUITING

Ankara, 06170, Turkey (Türkiye)
Local Institution - 0062
WITHDRAWN

Sofia, 1797, Bulgaria
Local Institution - 0065
WITHDRAWN

Cincinnati, Ohio, 45229, United States
Local Institution - 0066
WITHDRAWN

Cleveland, Ohio, 44109, United States
Local Institution - 0069
NOT_YET_RECRUITING

Sofia, 1309, Bulgaria
Local Institution - 0072
NOT_YET_RECRUITING

Curitiba, Paraná, 80250-060, Brazil
Local Institution - 0073
NOT_YET_RECRUITING

Vila Clementino, São Paulo-SP, 04038-002, Brazil
Local Institution - 0074
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100020, China
Praxis Kinder- und Jugendrheumatologie Dr. Ivan Foeldvari
RECRUITING

Hamburg, 22081, Germany
Santa Casa Instituto de Pesquisa
RECRUITING

São Paulo, 01223-001, Brazil
Santa Casa de Misericordia de Belo Horizonte
RECRUITING

Belo Horizonte, Minas Gerais, 30150-221, Brazil
Sc Medaudio-Optica Srl
RECRUITING

Râmnicu Vâlcea, Vâlcea County, 247065, Romania
Spitalul Clinic de Urgenta pentru Copii Cluj-Napoca
RECRUITING

Cluj-Napoca, Cluj, 400177, Romania
The Children's Hospital of Chongqing Medical University
RECRUITING

Chongqing, Chongqing Municipality, 400065, China
The Children's Hospital of Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310057, China
The First Hospital of Jilin University
RECRUITING

Changchun, Jilin, 130000, China
Umraniye Training and Research Hospital
RECRUITING

Istanbul, 34766, Turkey (Türkiye)
University Multiprofile Hospital for Active Treatment "Sveti Georgi" EAD
RECRUITING

Plovdiv, 4002, Bulgaria
University of Naples Federico II
RECRUITING

Naples, Campania, 80131, Italy

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