A smoother path to whiter teeth? testing a Pre-Bleaching paste
NCT ID NCT07770373
First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time
Summary
This trial tests whether applying a prophylaxis paste with or without desensitizing agents before in-office teeth whitening can reduce tooth sensitivity while still achieving the desired color change. Adults with discolored teeth but otherwise good oral health will receive one of the two pastes prior to bleaching. Researchers will measure color change using a spectrophotometer and assess pain intensity using a visual analog scale.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Prophylaxis paste with or without desensitizing agents applied before in-office tooth bleaching
- What this could lead to
- If effective, this could point to a way to make professional teeth whitening more comfortable by reducing sensitivity without compromising the whitening result.
- What could go wrong
- This is a small, early-stage trial, so results may not apply to everyone. The desensitizing paste might not reduce sensitivity or could slightly affect the whitening outcome.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 38 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients who have discolored teeth, minimum of 20 natural teeth, good oral hygiene, do not have any systemic disease. Exclusion Criteria: * Patients who have extensive prosthesis or restoration, tetracycline discoloration or fluorosis, endodontically treated teeth or gingival recession, smokers, periodontal disease, pregnant or lactating.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.