New stent aims to seal brain aneurysms safely

NCT ID NCT05543447

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a device called DERIVO 2heal, a small mesh tube placed in an artery to block blood flow into a brain aneurysm. The goal is to see if it safely and effectively seals the aneurysm over the medium and long term. About 158 adults with brain aneurysms will be enrolled, and researchers will track outcomes like complete aneurysm closure and any strokes or complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DERIVO 2heal Embolisation Device (a flow-diverting stent placed in the artery to block blood flow to the aneurysm)

What this could lead to

If successful, this device could offer a safer, more effective way to treat brain aneurysms and reduce the risk of rupture or stroke.

What could go wrong

This is a mid-stage study with 158 participants, so results may not apply to everyone. Risks include stroke, bleeding, or device-related complications like blood clots.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aneurysm brain aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charité - Universitätsmedizin Berlin

    RECRUITING

    Berlin, Germany

    Contact

  • Klinikum Bremerhaven-Reinkenheide

    RECRUITING

    Bremerhaven, Germany

    Contact

  • Klinikum Vest - Knappschaftskrankenhaus Recklinghausen

    RECRUITING

    Recklinghausen, Germany

    Contact

  • Krankenhaus Nordwest Frankfurt

    RECRUITING

    Frankfurt am Main, Germany

    Contact

  • Ludwig-Maximilians-Universität München

    RECRUITING

    München, Germany

    Contact

  • Mühlenkreiskliniken | Johannes Wesling Klinikum Minden

    RECRUITING

    Minden, Germany

    Contact

  • Städtisches Klinikum Solingen

    RECRUITING

    Solingen, Germany

    Contact

  • Technische Universität München

    RECRUITING

    München, Germany

    Contact

  • Universitätsklinikum Augsburg

    RECRUITING

    Augsburg, Germany

    Contact

  • Universitätsklinikum Carl Gustav Carus Dresden

    RECRUITING

    Dresden, Germany

    Contact

  • Universitätsklinikum Düsseldorf

    RECRUITING

    Düsseldorf, Germany

    Contact Email: •••••@•••••

  • Universitätsklinikum Essen

    RECRUITING

    Essen, Germany

    Contact

  • Universitätsklinikum Hamburg-Eppendorf

    RECRUITING

    Hamburg, Germany

    Contact

  • Universitätsklinikum Köln

    RECRUITING

    Cologne, Germany

    Contact

  • Universitätsklinikum Magdeburg

    RECRUITING

    Magdeburg, Germany

    Contact Email: •••••@•••••

  • Universitätsmedizin Halle

    RECRUITING

    Halle, Germany

    Contact

  • Westpfalz-Klinikum Kaiserslautern

    RECRUITING

    Kaiserslautern, Germany

    Contact