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Could your own tooth help your jawbone heal faster?

NCT ID NCT07798206

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This trial tests whether placing a graft made from the patient's own tooth and blood components into an extraction socket improves bone healing compared with letting the socket heal on its own. Adults with non-restorable teeth will receive either the graft or no graft, and researchers will measure new bone formation and density after three months. The goal is to see if this natural approach can support better healing for future dental work.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A mix of ground dentin from the extracted tooth and platelet-rich fibrin (PRF) made from the patient's blood, placed into the extraction socket to promote bone healing.
What this could lead to
If it works, this approach could speed up and improve bone healing after tooth extraction, potentially making future dental implants more successful.
What could go wrong
This is a small, early-stage trial, so the benefits are uncertain. The procedure involves surgery and may carry risks like infection or incomplete healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

45 people

The number who actually took part.

Started

Jan 2023

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. Patients with hopeless non molar teeth that need extraction. 2. Age above 18 years. 3. Generally good state of health. 4. Agreement to participate in the study and also have to be able to attend postoperative clinical and radiological follow-up 6. Acquisition of informed consent. Exclusion Criteria: * 1- Patients refuse to be enrolled in this study 2- Patients with uncontrolled systemic disease. 3- Previously diagnosed hematological and neurological conditions.

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Conditions

The condition(s) this trial relates to.

alveolar periostitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dentine autograft in extraction socket PRF in extraction socket

Contacts and locations

Locations

  • Faculty of Dentistry, Cairo University

    Cairo, Cairo Governorate, 11553, Egypt