Cold therapy and fluoride may ease dental pain for kids with enamel defect

NCT ID NCT07326241

First seen Jan 11, 2026 · Last updated Jun 18, 2026 · Updated 27 times

Summary

This study looks at two simple treatments—silver diamine fluoride (a liquid applied to teeth) and intraoral cryotherapy (a cold application inside the mouth)—to see if they can help reduce pain during dental procedures for children aged 6 to 12 who have a condition called Molar-Incisor Hypomineralization (MIH). MIH causes weak, porous enamel that often leads to tooth sensitivity and makes numbing less effective. The goal is to make dental visits more comfortable and less stressful for these children.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mersin University, School of Dentistry

    Mersin, Turkey (Türkiye)

  • Çanakkale Onsekiz Mart University, School of Dentistry

    Çanakkale, Turkey (Türkiye)

Conditions

The condition(s) this trial relates to.

Molar Hypomineralization myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.