New drug combo aims to shrink hard-to-treat stomach cancers

NCT ID NCT07546812

First seen Apr 25, 2026 · Last updated May 09, 2026 · Updated 1 time

Summary

This study tests a new drug called denikitug, alone or with other treatments, in people with advanced HER2-negative stomach, gastroesophageal junction, or esophageal cancer that has spread or come back after initial therapy. About 120 participants will be randomly assigned to receive denikitug by itself or combined with nivolumab or chemotherapy. The main goal is to see if these treatments can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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