Brain zaps for depression? tiny trial hopes to lift the fog
NCT ID NCT01798407
First seen Dec 17, 2025 · Last updated May 14, 2026 · Updated 26 times
Summary
This small pilot study tests whether deep brain stimulation (DBS) targeting a specific brain region called the lateral habenula can safely help people with severe, treatment-resistant depression. Six adults with either major depressive disorder or bipolar I disorder who have been depressed for at least two years will receive the implant. The main goal is to see if depression scores improve by at least 50% after six months of stimulation.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
Conditions
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