Could a Pre-Treatment boost Chemo's power against tough leukemia?
NCT ID NCT01627041
First seen Oct 31, 2025 · Last updated Apr 28, 2026 · Updated 26 times
Summary
This study tests whether adding a drug called decitabine before standard chemotherapy can help more people with acute myeloid leukemia (AML) achieve remission. About 178 adults with AML that is not the most treatable type will receive either a low or high dose of decitabine followed by chemo. The goal is to see if this approach improves complete remission rates and long-term survival.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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Lafayette Family Cancer Center-EMMC
Brewer, Maine, 04412, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467, United States
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Montefiore Medical Center-Weiler Hospital
The Bronx, New York, 10461, United States
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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
New York, New York, 10032, United States
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NYP/Weill Cornell Medical Center
New York, New York, 10065, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
Conditions
Explore the condition pages connected to this study.