Experimental cancer drug trial halted early: what it means for patients
NCT ID NCT04892017
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 34 times
Summary
This early-stage study tested a new drug called DCC-3116, alone or with other targeted therapies, in people with advanced solid tumors that have certain gene mutations (RAS/MAPK pathway). The trial was terminated early, so results are limited. It involved 91 participants and aimed to find safe doses and see if the drug could shrink tumors.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Laura & Isaac Perlmutter Cancer Center at NYU Langone Health
New York, New York, 10016, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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NEXT Oncology
Austin, Texas, 78758, United States
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NEXT Oncology
San Antonio, Texas, 78229, United States
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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Rutgers Cancer Institute
New Brunswick, New Jersey, 08901, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University of Wisconsin Clinical Science Center
Madison, Wisconsin, 53792, United States
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Washington University Siteman Cancer Center
St Louis, Missouri, 63108, United States
Conditions
Explore the condition pages connected to this study.